نتایج جستجو برای: longevity predicting

تعداد نتایج: 149344  

حسن‌پور اصیل, معظم , روئین, زینب , صبوری, عاطفه ,

Chrysanthemum is one of the most important ornamental and medicinal plants in the world. In this study, diversity among 50 genotypes of chrysanthemum morifolium was analyzed using phenologic and morphologic traits. The variation between studied genotypes showed a significant difference for all traits and coefficient of genetic variations for most traits was greater than 40%. The highest general...

2017
Sriram Gubbi Nir Barzilai Jill Crandall Joe Verghese Sofiya Milman

BACKGROUND Individuals with exceptional longevity and their offspring manifest a lower prevalence of age-related diseases than families without longevity. However, the contribution of dietary habits to protection from disease has not been systematically assessed in families with exceptional longevity. OBJECTIVE The aim of this study is to compare dietary patterns between individuals with pare...

2015
Stewart Frankel Jared Woods Tahereh Ziafazeli Blanka Rogina

Single-gene mutations that extend longevity have revealed regulatory pathways related to aging and longevity. RPD3 is a conserved histone deacetylase (Class I HDAC). Previously we showed that Drosophila rpd3 mutations increase longevity. Here we tested the longevity effects of RPD3 on multiple nutrient levels. Dietary restriction (DR) has additive effects on RPD3-mediated longevity extension, b...

Journal: :The journals of gerontology. Series A, Biological sciences and medical sciences 2015
Linda Broer Aron S Buchman Joris Deelen Daniel S Evans Jessica D Faul Kathryn L Lunetta Paola Sebastiani Jennifer A Smith Albert V Smith Toshiko Tanaka Lei Yu Alice M Arnold Thor Aspelund Emelia J Benjamin Philip L De Jager Gudny Eirkisdottir Denis A Evans Melissa E Garcia Albert Hofman Robert C Kaplan Sharon L R Kardia Douglas P Kiel Ben A Oostra Eric S Orwoll Neeta Parimi Bruce M Psaty Fernando Rivadeneira Jerome I Rotter Sudha Seshadri Andrew Singleton Henning Tiemeier André G Uitterlinden Wei Zhao Stefania Bandinelli David A Bennett Luigi Ferrucci Vilmundur Gudnason Tamara B Harris David Karasik Lenore J Launer Thomas T Perls P Eline Slagboom Gregory J Tranah David R Weir Anne B Newman Cornelia M van Duijn Joanne M Murabito

BACKGROUND The genetic contribution to longevity in humans has been estimated to range from 15% to 25%. Only two genes, APOE and FOXO3, have shown association with longevity in multiple independent studies. METHODS We conducted a meta-analysis of genome-wide association studies including 6,036 longevity cases, age ≥90 years, and 3,757 controls that died between ages 55 and 80 years. We additi...

Journal: :American journal of human biology : the official journal of the Human Biology Council 2011
Loredana Castrì Lorena Madrigal Mauricio Melendez-Obando Ramon Villegas-Palma Ramiro Barrantes Henriette Raventos Reynaldo Pereira Donata Luiselli Davide Pettener

OBJECTIVE To determine if individuals who carry mitochondrial markers which have been previously shown to affect longevity also have differential lifetime reproductive success (LRS). METHODS We extracted the mtDNA from living subjects residing in Atenas, Costa Rica. Since mtDNA does not recombine, and its probability of mutation is low, we assume that all maternal ancestors of the living subj...

Journal: :PLoS Genetics 2009
Russell Bell Alan Hubbard Rakesh Chettier Di Chen John P. Miller Pankaj Kapahi Mark Tarnopolsky Sudhir Sahasrabuhde Simon Melov Robert E. Hughes

We have mapped a protein interaction network of human homologs of proteins that modify longevity in invertebrate species. This network is derived from a proteome-scale human protein interaction Core Network generated through unbiased high-throughput yeast two-hybrid searches. The longevity network is composed of 175 human homologs of proteins known to confer increased longevity through loss of ...

2013
Anthony M. Gould Mélanie Robert

Neoliberalism, or faith in the capacity of markets to solve social and economic problems, is a key element of the prevailing public policy orthodoxy in G20 countries. Throughout the 1980s, key proponents of the Neoliberal message such as UK Prime Minister Margaret Thatcher and American President Ronald Regan spoke optimistically about the philosophy’s inevitability and its benefits. During that...

2001
Howard Swatland

The pH of meat has a strong effect on both light scattering (paleness) and water-holding capacity (WHC), using WHC imprecisely as a general term to describe fluid distribution and retention. Light scattering has many attributes in meat (in relation to wavelength, direction and polarization), and is easier to measure on a routine basis than pH. Thus, the indirect correlation of light scattering ...

Journal: :Management Science 2011
David A. Schweidel Eric T. Bradlow Peter S. Fader

Multi-service providers, such as telecommunication and financial service companies, can benefit from understanding how customers’ service portfolios evolve over the course of their relationships. This can provide guidance for managerial issues such as customer valuation and predicting customers’ future behavior, whether it is acquiring additional services, selectively dropping current services,...

1999
S. Gross

Seasonal variations in the Earth’s gravitational field arc investigated through the analysis of LAGEOS I satellite laser ranging measurements and are compared with those produced by atmospheric mass redistribution as inferred from global surface pressure data from the National Centers for Environmental Prediction (NCEP) reanalyses. The effect of oceanic tides and groundwater are considered as w...

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