نتایج جستجو برای: low bone mass

تعداد نتایج: 1866945  

2005
Helen M Buntain Philip J Schluter Scott C Bell Ristan M Greer Joseph C.H. Wong Jennifer Batch Peter Lewindon Claire E Wainwright

Objective: To observe the gains in bone mass in children and adolescents with cystic fibrosis (CF) over 24 months and examine the relationship between areal bone mineral density (aBMD) and associated clinical parameters including physical activity, nutrition and 25-hydroxyvitamin D (25OHD). Methods: Areal BMD of the total body (TB), lumbar spine (LS) and total femoral neck (FNt) were repeatedly...

Doaa Ghareeb, Fatma H El-Rashidy Sherif El-Mallawany

This study aimed to explore and validate a new juvenile osteopenic (JO) rat model then examine the efficacy of moghat (Glossostemon bruguieri) as an alternative reversal therapy for JO. Phytochemical screening analysis showed that moghat contains 5.8% alkaloids, 1.5% flavonoids and 13.2% total phenols. Juvenile osteopenia was induced in 15 days old Sprague- Dawley female rats by feeding them fr...

2005
Helen M Buntain Philip J Schluter Scott C Bell Ristan M Greer Joseph C.H. Wong Jennifer Batch Peter Lewindon Claire E Wainwright Helen Buntain Joseph Wong

Objective: To observe the gains in bone mass in children and adolescents with cystic fibrosis (CF) over 24 months and examine the relationship between areal bone mineral density (aBMD) and associated clinical parameters including physical activity, nutrition and 25-hydroxyvitamin D (25OHD). Methods: Areal BMD of the total body (TB), lumbar spine (LS) and total femoral neck (FNt) were repeatedly...

Journal: :The Journal of clinical endocrinology and metabolism 2003
Madhusmita Misra Leslie A Soyka Karen K Miller David B Herzog Steven Grinspoon Dave De Chen Gregory Neubauer Anne Klibanski

Low bone mineral density (BMD) in adolescents with anorexia nervosa (AN) is associated with a low bone turnover state. Osteoprotegerin (OPG), a cytokine that acts as a decoy receptor for receptor activator of nuclear factor-kappaB ligand, decreases bone resorption by inhibiting differentiation of osteoclast precursors and activation of mature osteoclasts, and by stimulating osteoclast apoptosis...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2005
Philippe Clément-Lacroix Minrong Ai Frederic Morvan Sergio Roman-Roman Béatrice Vayssière Cecille Belleville Kenneth Estrera Matthew L Warman Roland Baron Georges Rawadi

One of the well characterized cell biologic actions of lithium is the inhibition of glycogen synthase kinase-3beta and the consequent activation of canonical Wnt signaling. Because deficient Wnt signaling has been implicated in disorders of reduced bone mass, we tested whether lithium could improve bone mass in mice. We gavage-fed lithium chloride to 8-week-old mice from three different strains...

Journal: :Journal of Orthopaedics, Trauma and Rehabilitation 2012

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