Animal experimental studies indicate that acute or chronic low-dose ionizing radiation (LDIR) (≤100 mSv) or low-dose-rate ionizing radiation (LDRIR) (<6 mSv/h) exposures may be harmful. It induces genetic and epigenetic changes and is associated with a range of physiological disturbances that includes altered immune system, abnormal brain development with resultant cognitive impairment, catarac...

BACKGROUND Although high doses of ionizing radiation have long been linked to circulatory disease, evidence for an association at lower exposures remains controversial. However, recent analyses suggest excess relative risks at occupational exposure levels. OBJECTIVES We performed a systematic review and meta-analysis to summarize information on circulatory disease risks associated with modera...

Objectives In recent years, the application of radiopharmaceuticals in nuclear medicine has increased substantially. Following the diagnostic procedures performed in nuclear medicine departments, such as myocardial perfusion imaging, patients generally receive considerable doses of radiation. Normally, radiation-induced DNA damages are expected following exposure to a low-dose ionizing radiatio...

Background: Exposure to&nbsp;ionizing&nbsp;radiation is known to have various effects on hematological parameters of&nbsp;biological&nbsp;sample. This study was aimed at evaluating the effect of&nbsp;ionizing&nbsp;radiation on some hematological parameters in guinea pigs. Materials and Methods: Thirty-six (36) apparently healthy adult guinea pigs of both sexes weighing between 700g &ndash; 1200...

background: the specific antibody response against newcastle disease virus (ndv) in the blood serum of chickens hatched from eggs exposed to low dose gamma-radiation was studied. materials and methods: two groups of eggs of commercial meat chicken lines were irradiated with the dose of 0.30 gy 60co gamma-rays before incubation and on the 19th day of incubation, respectively. the same number of ...

Mark P. Little, DPhil Richard Wakeford, PhD E. Janet Tawn, PhD Simon D. Bouffler, PhD Amy Berrington de Gonzalez, DPhil Deterministic and stochastic effects associated with high-dose ionizing radiation (x-ray) exposure have been known for almost as long as ionizing radiation itself (1–3). At lower doses, radiation risks are primarily stochastic effects, in particular, somatic effects (cancer) r...

INTRODUCTION Modulation of gene expression in response to ionizing radiation is of prime interest in the field of radiation biology. In most articles concerning biological responses to ionizing radiation, the findings of radiation-induced gene expression after irradiation at a lethal dose range (2-50 Gy) has been reported. Recently, the biological effect of low dose radiation on cellular respon...

Ionizing radiation has been successfully used in medical tests and treatment therapies for a variety of medical conditions. However, patients and health-care workers are greatly concerned about overexposure to medical ionizing radiation and possible cancer induction due to frequent mammographies and/or CT scans. Diagnostic imaging involves the use of low doses of ionizing radiation, and its pot...

In Pakistan the Siwalik region is exposed to ionizing radiation (IR) from uranium mineralization. The current research describes the impact of long-term low-dose terrestrial ionizing radiation exposure on the hematopoietic indices of the region’s inhabitants. Mean values of the selected complete blood count (CBC) parameters were calculated to examine low or high trend. A t-test was conducted on...

background: study of vascular and its secretory profile changes is an important issue in pathogenesis of radiation myelopathy. this paper reports the prostacyclin concentration changes after low-moderate doses of x-irradiation within a short period of time. materials and methods: cervical cords of wistar rats were irradiated to doses of 0.5, 1, 2, 4 and 6 gy x-rays. after 24 hours, 2 and 13 wee...