The clinical manifestations of lipodystrophy syndromes (LS) are hypoleptinemia, hyperglycemia, insulin resistance, dyslipidemia and hepatic steatosis. Leptin replacement therapy (LRT) is effective at improving these pathologies. Currently, there are no data compiling the evidence from the literature, and demonstrating the effect of LRT in LS patients. A systematic review of the MEDLINE and Coch...

Saat ini, Bus Rapid Transit (BRT) Bandar Lampung tidak memiliki informasi mengenai lokasi BRT. Ketiadaan BRT menyebabkan pengguna merasa kesulitan dan memilih angkutan umum lainnya. Dari hasil survey yang dilakukan, banyak membutuhkan untuk mengetahui estimasi waktu ke halte. Sehingga dibangun aplikasi menjawab kebutuhan pengguna. Penelitian ini dilakukan dengan menggunakan metode extreme progr...

Among critically ill patients with lower respiratory tract (LRT)-confirmed influenza, we retrospectively observed worse 28-day clinical outcomes in upper respiratory tract (URT)-negative versus URT-positive subjects. This finding may reflect disease progression and highlights the need for influenza testing of both URT and LRT specimens to improve diagnostic yield and possibly inform prognosis.

Recent molecular diagnostic methods have significantly improved the diagnosis of viral pneumonia in intensive care units (ICUs). It has been observed that 222G/N changes in the HA gene of H1N1pdm09 are associated with increased lower respiratory tract (LRT) replication and worse clinical outcome. In the present study, the frequency of respiratory viruses was assessed in respiratory samples from...

In pathological states, repetitive inputs from the ascending pathways involved in the genesis and integration of nociception, leads to molecular, anatomical and electrophysiological adaptive changes of these pathways, contributing to the development of pain chronicity. In the past, neurotrophic factors have been implicated in neuronal plasticity in adult central nervous system. We have previous...

In this paper we propose a soft-hard combination scheme, called SHC scheme, for cooperative spectrum sensing in cognitive radio networks. The SHC scheme deploys a cluster based network in which Likelihood Ratio Test (LRT)-based soft combination is applied at each cluster, and weighted decision fusion rule-based hard combination is utilized at the fusion center. The novelties of the SHC scheme a...

The likelihood ratio test (LRT) and the related F test, popularized in astrophysics by Eadie et al. (1971), Bevington (1969), Lampton, Margon, and Bowyer (1976), Cash (1979), and Avni et al. (1978) do not (even asymptotically) adhere to their nominal χ and F distributions in many statistical tests common in astrophysics, thereby casting many marginal line or source detections and non-detections...

Intersections are considered as the most critical parts of the bus rapid transit (BRT) system. Transit signal priority is one of the efficient solutions to reduce BRT fleet delays at intersections. The aim of this study is to propose a new algorithm to decrease the BRT fleet delays at actuated intersections, while reducing the negative impacts on different approaches. The adaptive strategy is a...