Interstitial lung disease (ILD) in infants and children comprises a large spectrum of rare respiratory disorders that are mostly chronic and associated with high morbidity and mortality. These disorders are characterized by inflammatory and fibrotic changes that affect alveolar walls. Typical features of ILD include dyspnea, diffuse infiltrates on chest radiographs, and abnormal pulmonary funct...

ERS hosted a 3-day course on interstitial lung diseases in Heidelberg, Germany http://ow.ly/M8MD3021q6n.

Fibrosis is fundamental to the pathogenesis of many chronic lung diseases, including some lung infections, airway diseases such as bronchiectasis and asthma, and most of the diffuse parenchymal lung diseases. Idiopathic pulmonary fibrosis, the prototypical fibrotic lung disease, is amongst the most common diffuse parenchymal lung diseases and is characterized by progressive decline in lung func...

respiratory diseases are considered as common disorders in broiler farms. over the past decade a pleomorphic gram negative bacteria which isolated from broilers with respiratory diseases now calls ornithobacterium rhinotracheale . in this study, samples from trachea and lung collected from chicken with clinical respiratory signs in 173 broiler farms and then subjected on bacterial culture. the ...

Accessible online at: http://BioMedNet.com/karger In the present issue of Respiration, Quadrelli and Roncoroni [1] compare characteristics of asthma between 99 younger patients and 50 elderly asthmatics. Their results suggest that the severity of asthma increases with age and that the increase in severity is related to the duration of the disease rather than to age itself: severity is greater i...

aspergillus spp. are ubiquitous saprophytic fungi that cause a variety of diseases, ranging from hypersensitivity reactions to flulike pneumonia and life-threatening invasive aspergillosis. as the lung is the primary site of initial infection with airborne conidia, we investigated the innate immune responses of bronchial epithelial cells against different forms of aspergillus spp.

Fibrosing lung disorders include a large number of diseases with diverse behaviour. Patients can die because of the progression of their illness, remain stable or even improve after appropriate treatment has been instituted. Comorbidities, such as acute and chronic infection, gastro-oesophageal reflux, pulmonary hypertension, lung cancer, cardiovascular diseases, and obstructive sleep apnoea, c...

For many years has been well known that smoking could cause lung damage. Chronic obstructive pulmonary disease and lung cancer have been the two most common smoking-related lung diseases. In the recent years, attention has also focused on the role of smoking in the development of interstitial lung diseases (ILDs). Indeed, there are three diseases, namely respiratory bronchiolitis-associated ILD...

In general, the first approach to a histological diagnosis is the categorization of morphological findings according to the current standard into ontogenetic, circulatory, inflammatory, tumor-like, and neoplastic lesions. Furthermore, it needs to be addressed if and to which extent specific changes are evident in defined anatomical structures such as the pleura, the alveolae and their structure...

The development of different molecular biology techniques in the past decade has led to an explosion of new research in molecular pathology with consequent important applications to diagnosis, prognosis, and therapeutics, as well as a clearer concept of the disease pathogenesis. Many methods used in molecular pathology are now validated and used in several areas of pathological diagnosis, parti...