Abstract Funding Acknowledgements Type of funding sources: None. Introduction Adults with repaired aortic coarctation (CoA) require lifelong follow-up due to late complications, including left ventricular (LV) myocardial dysfunction. Age at the time CoA repair is an important prognostic factor in these patients (pts). Purpose To evaluate LV size, ejection fraction (EF) and global longitudinal s...

The theory of respectively interpretation proposed in Yatabe and Tam (2021) "In defense an HPSG-based non-constituent coordination" (Linguistics Philosophy 44, pp. 1-77) entails that Binding Conditions A B need to be formulated as constraints on the form semantic representations. It is possible formulate two binding conditions such if anaphoric relations are encoded representations a way analog...

Aim of the work To study extent right ventricular (RV) dysfunction in ischemic patients after coronary artery bypass grafting (CABG). Patients and methods RV function was studied preoperatively followed for 1 month postoperatively 40 who were scheduled elective surgery other controls. We evaluated by tissue Doppler tricuspid annulus basal septum, annular plane systolic excursion, dimensions. Bo...

BACKGROUND Xenon has only minimal haemodynamic side-effects on normal myocardium and might be a preferable anaesthetic agent for patients with heart failure. We studied the haemodynamic changes caused by 70% xenon in rabbits with chronically compromised left ventricular (LV) function. METHODS Anaesthetized rabbits were thoracotomized and a major coronary artery was ligated to induce ischaemic...

UNLABELLED The aim of this study was to evaluate LV function, by means of echocardiography, after mitral valve repair (MVr) or mitral valve replacement (MVR) in patients (pts) with chronic degenerative mitral regurgitation (MR) and depressed LV systolic function during a 6-years follow-up (FU) period. PATIENTS AND METHODS Forty-five pts with moderately severe or severe MR and preoperative EF<...

Dilated cardiomyopathy (DCM) is characterized by left ventricular dilation and cardiac fibrosis. Emerging evidence indicated that endothelial‑to‑mesenchymal transition (Endo‑MT) is a crucial event during organ fibrosis. This study was performed to clarify whether Endo‑MT contributed to the progression of cardiac fibrosis in DCM. Cardiac samples from patients with DCM and control were obtained. ...

OBJECTIVES While the results of mitral repair in ischaemic mitral regurgitation have been repeatedly reported, less data are available about the outcome of surgical repair of functional mitral regurgitation (FMR) in idiopathic dilated cardiomyopathy (iDCM) which represents the topic of this study. METHODS Fifty-four iDCM patients (mean age 63 ± 10.5 years) underwent mitral valve repair for se...

BACKGROUND To study the role of Parkin in the regulation of mitochondrial autophagy in the heart by assessing mitochondrial autophagy and changes in Parkin protein expression in rat myocardium after myocardial infarction (MI). MATERIAL AND METHODS Rats were randomly assigned to three groups: control, sham, and MI. Four weeks after induction of MI, ultrasonic examination of the rats was performe...

BACKGROUND Approximately 30% of patients treated with cardiac resynchronization therapy (CRT) do not achieve favourable response. The purpose of the present study was to identify echocardiographic and clinical predictors of a positive response to CRT. METHODS The study included 82 consecutive heart failure (HF) patients in New York Heart Association (NYHA) functional class III or IV with left...