Locally tailored interventions for neglected tropical diseases (NTDs) are becoming increasingly important ensuring that the World Health Organization (WHO) goals control and elimination reached. Mathematical models, such as those developed by NTD Modelling Consortium, able to offer recommendations on but remain constrained data currently available. Data collection NTDs needs be strengthened bet...

Research on tumor-induced lymphangiogenesis has predominantly focused on alterations and abnormal growth of peritumoral and intratumoral lymphatic vessels. However, recent evidence indicates that lymphangiogenesis of sentinel lymph nodes might also contribute to cancer progression. In clinical oncology, the sentinel lymph nodes play an important r...

Lymphangioma circumscriptum is a congenital lymphatic malformation that results in gradual dilatation of lymphatic vessels and development of lymphatic cisterns. The treatment of choice is radical surgery. Other treatment methods including cryotherapy, sclerosing agent injections, radiation therapy and CO2 laser were suggested. We report successful treatment of a 14-year-old boy affected with l...

Chylous ascites, defined as a lipid-rich fluid accumulation in the peritoneal cavity, is a rare pathology of the lymphatic system and is a very rare cause of acute abdomen. It is generally associated with diseases such as cancer, cirrhosis, inflammatory diseases, surgery, or trauma. In this study, we report a patient with chylous ascites, which mimics acute appendicitis. Diagnosis and treatment...

Skin failure is managed by physician belonging to the profession of Dermatology that has had several years of additional training in the diagnosis and management of skin diseases. There are also wound healers, lymphoedema managers,employees of burns units, and custodians of neglected tropical skin diseases such as, for example, leprosy, leishmaniasis,onchocerciasis, lymphatic filariasis, yaws a...

Emergence and resurgence of mosquito-borne diseases such as malaria, dengue, Japanese encephalitis and filariasis both in tropical and subtropical regions are well known. It is estimated that 500 million – one in every ten persons suffer from one or more tropical diseases and the global situation of lymphatic filariasis is reported as the 4th rank1.. The geo-climatic conditions in India are con...

The lymphatic vasculature is essential for tissue fluid homeostasis and cancer metastasis, although the molecular mechanisms involved remain poorly characterized. Endothelin-1 (ET-1) axis plays a crucial role in angiogenesis and tumorigenesis. Here, we first report that ET-1 acts as a lymphangiogenic mediator. We performed in vitro and in vivo studies and show that lymphatic endothelial cells p...

Lymphatic vascular system is a relatively rare focus of the modern cardiovascular research. In this context, the paper published by Greiwe et al. (2015)in this journal seems to represent a very important body of new evidence concerning the influence of different training regimens on lymphangiogenesis and lymphatic vessel densities in skeletal muscles and myocardium. The lymphatic system has imp...