Opiates and related molecules are medically essential, but their production via field cultivation of opium poppy Papaver somniferum leads to supply inefficiencies and insecurity. As an alternative production strategy, we developed baker's yeast Saccharomyces cerevisiae as a microbial host for the transformation of opiates. Yeast strains engineered to express heterologous genes from P. somniferu...

– Despite some research on self-management and self-organization, the control and the coordination of an organization without hierarchy remains a mysterious phenomenon. However, the dissemination of the responsibilities and the decentralized decisions in a business network require improving our knowledge in this field. From this theoretical point of view, our article aims to explore the modes o...

Electrostatic Discharge (ESD) is generally recognized as an increasingly important issue for modern integrated circuits. Thinner gate oxides, complex chips with multiple power supplies and/or mixed-signal blocks, larger chip capacitance and faster circuit operation all contribute to increased ESD-sensitivity of advanced semiconductor products [1]. Detailed understanding of complex circuit-devic...

Knowledge management facilitates the firms and employees to deliver better products and services and hence achieve competitive advantages and profits. The issues of knowledge management have drawn much attention form industry and academia. However, few reports have been found available investigating how knowledge management is adopted and diffused in organizations. This paper adopts structural ...

ABSTRACT In the past few years, dairy industry has become one of the fastest growing sectors in the packaged food industry of Vietnam. However, the value-added creation among different activities in the value chain of Vietnam dairy sector is distributed unequally. In the production activities, the dairy farmers gain low value-added rate due to high input cost. Whereas the processing activities,...

A high performance liquid chromatography (HPLC) method for simultaneous analysis of venlafaxine and its major metabolite 0-desmethylvenlafaxine and vilazodone and its methabolite M10 have been devel- oped and validated. Chromatography was performed on the Phenyl-Hexyl column with mobile phase containing methanol, acetate buffer at pH 3.5 and diethylamine. The application of stationary phase wit...

A new azaphilonidal derivative, monapurpyridine A (MPA), has recently been isolated from the fermented products of Monascus purpureus NTU 568. The structure of MPA was elucidated by nuclear magnetic resonance (1H-NMR, 13C-NMR, COSY, HMQC, and HMBC) and other spectroscopic analyses. Biological evaluation revealed that MPA could induce cell death in human breast adenocarcinoma cells MCF-7, and it...