The treatment of malignant glioma is currently ineffective. Oncolytic viruses are being explored as a means to selectively lyse tumor cells in the brain. We have engineered a mutant herpes simplex virus type 1 with deletions in the viral UL39 and g134.5 genes and an insertion of the two prodrug activating genes, CYP2B1 and secreted human intestinal carboxylesterase . Each of these can convert t...

Apart from a reflecting and a transparent state, rare-earth-Mg alloys ~RE-Mg! exhibit also a highly absorbing, black state during loading with hydrogen. The occurrence of such a black state is due to the disproportionation into subwavelength size REH21e and Mg grains during the first hydrogen loading. While the optical properties of REHx change continuously with a further increase in hydrogen c...

The treatment of malignant glioma is currently ineffective. Oncolytic viruses are being explored as a means to selectively lyse tumor cells in the brain. We have engineered a mutant herpes simplex virus type 1 with deletions in the viral UL39 and gamma(1)34.5 genes and an insertion of the two prodrug activating genes, CYP2B1 and secreted human intestinal carboxylesterase. Each of these can conv...

Kinetics of hydrogen absorption and desorption reactions was investigated on the MgH2 composite doped with 1 mol% Nb2O5 as a catalyst by ballmilling. The composite after dehydrogenation at 200 °C absorbed gaseous hydrogen of ~ 4.5 mass% even at room temperature under lower pressure than 1 MPa within 15 sec and finally its capacity reached more than 5 mass%. On the other hand, the catalyzed MgH2...

The structures of NADP+ and magnesium isocitrate bound to the NADP(+)-dependent isocitrate dehydrogenase of Escherichia coli have been determined and refined at 2.5-A resolution. NADP+ is bound by the large domain of isocitrate dehydrogenase, a structure that has little similarity to the supersecondary structure of the nucleotide-binding domain of the lactate dehydrogenase-like family of nucleo...

A high-energy ball-milling method was applied for different milling times (1 h, 3 and 10 h) to synthetize nanocrystalline MgH2 powder samples catalyzed by Fe2Ti. Morphology microstructure of the powders were characterized scanning electron microscopy X-ray diffraction. The recorded diffraction profiles evaluated convolutional multiple whole profile fitting algorithm, in order determine microstr...

Development of catalysts with highly efficient catalytic performance has a significant status in accelerating the MgH2 hydrogen storage system. In this work, we report Na2Ti3O7 catalyst rich oxygen vacancies (Na2Ti3O7-Ov), which was synthesized from Ti3C2-MXene, and confirm remarkable enhancement to MgH2. Expressly, initial dehydrogenation temperature + 5Na2Ti3O7-Ov (an addition 5 wt % Na2Ti3O7...