The aim of the present work is first to synthesis a magnetic chitosan hydrogel (chitosan ferrogel) using blending method and second study it rheological behavior. Magnetic components ( maghemite particles γ-Fe2O3 ) were synthesized via simple chemical co-precipitation route also called Massart's procedure. Before being dispersed in network, covered with cationic polyelectrolyte (Polydiallyldime...

Composite chitosan-magnetite microparticles (Fe-Cc) were evaluated as a new adsorbent for cobalt and nickel ion separation from aqueous solutions. Sorption batch experiments were conducted for optimizing the pH, initial target ion concentration and adsorbent amount. The experimental data were fitted using Langmuir, Freundlich, and respectively DubininRadushkevich isotherm models. The Langmuir m...

Chitosan is widely applied in biomedical and cosmetic fields. For this reason, there is a need to modify this biopolymer to achieve new properties of chitosan-based materials. The properties of chitosan can be modified by several cross-linking methods. In this work, we used the chemical cross-linking of chitosan with tannic acid, after which cross-linked chitosan was shaped into a 3D structure ...

Polyelectrolyte-coated nanoparticles or microparticles interact with bioactive molecules (peptides, proteins or nucleic acids) and have been proposed as delivery systems for these molecules. However, the mechanism of adsorption of polyelectrolyte onto particles remains unsolved. In this study, cationic poly(lactide-co-glycolide) (PLGA) nanoparticles were fabricated by adsorption of various conc...

Chemical modification of chitosan is increasingly studied for its potential of providing new applications of chitosan. Here, a group of novel chitosan quaternary ammonium derivatives containing pyridine or amino-pyridine were designed and successfully synthesized through chemical modification of chitosan. Pyridine and amino-pyridine were used as functional groups to improve the antifungal activ...

BACKGROUND The purpose of this study was to develop a self-aggregated nanoparticulate vehicle using an amphiphilic poly(lactic acid)-grafted-chitosan (PLA-g-CS) copolymer and to evaluate its potential for ocular delivery of amphotericin B. METHODS A PLA-g-CS copolymer was synthesized via a "protection-graft-deprotection" procedure and its structure was confirmed by Fourier transform infrared ...

BACKGROUND Iron oxide nanoparticles are of considerable interest because of their use in magnetic recording tape, ferrofluid, magnetic resonance imaging, drug delivery, and treatment of cancer. The specific morphology of nanoparticles confers an ability to load, carry, and release different types of drugs. METHODS AND RESULTS We synthesized superparamagnetic nanoparticles containing pure iron...

Labeling of cells with nanoparticles for living detection is of interest to various biomedical applications. In this study, novel fluorescent/magnetic nanoparticles were prepared and used in high-efficient cellular imaging. The nanoparticles coated with the modified chitosan possessed a magnetic oxide core and a covalently attached fluorescent dye. We evaluated the feasibility and efficiency in...

This work examined the removal of Pb(II) using a chitosan derivative (SB, synthesized from benzaldehyde) assisted by a magnetic field. The adsorption capacity for Pb(II) was investigated. It was found that 1) the pH and concentration of the ion solution, as well as exposure time and strength of magnetic field, affected the degree of adsorption; and 2) studies of the adsorption isotherms and kin...

Iron oxide nanoparticles (IOs) are intrinsically theranostic agents that could be used for magnetic resonance imaging (MRI) and local hyperthermia or tissue thermal ablation. Yet, effective hyperthermia and high MR contrast have not been demonstrated within the same nanoparticle configuration. Here, magnetic nanoconstructs are obtained by confining multiple, ∼ 20 nm nanocubes (NCs) within a deo...