The localization of microbubbles to a treatment site has been shown to be essential to their effectiveness in therapeutic applications such as targeted drug delivery and gene therapy. A variety of different strategies for achieving localization has been investigated, including biochemical targeting, acoustic radiation force, and the incorporation of superparamagnetic nanoparticles into microbub...

Globally, leukemia and skin cancers are the most common types of cancers. However, current measures (radiation, chemotherapy, etc.) cannot exercise high accuracy when targeting such tumors cancers, causing extensive damage to surrounding tissue leading adverse effects commonly associated with treatments as chemotherapy. Magnetic drug delivery applies anticancer nanoparticles a component vehicle...

Human serum albumin labeled with technetium-99m was encapsulated together with magnetite particles into phosphatidylcholine/cholesterol liposomes. In order to investigate the stability of this complex and its ability to be used for magnetic drug targeting, the in-vivo distribution after intravenous administration in rats was estimated. For in-vivo targeting an SmCo permanent magnet with intensi...

Submit Manuscript | http://medcraveonline.com cellular and cellular based mechanisms of resistance and to increase selectivity of drugs [1]. In this way as an example, Wang et al. [2] reported that targeted magnetic nanoparticles containing 5-FU can improve the chemotherapeutic effect of 5-FU against hepatocellular carcinoma. Nanoparticles may be defined as colloidal systems (<1 μm), generally ...

This study demonstrated the fabrication of alginate microfibers using a modular microfluidic system for magnetic-responsive controlled drug release and cell culture. A novel two-dimensional fluid-focusing technique with multi-inlets and junctions was used to spatiotemporally control the continuous laminar flow of alginate solutions. The diameter of the manufactured microfibers, which ranged fro...