A significant increase in the incidence of male infertility has been described in the international literature, raising questions about its causes. Part of this effect may result from synthetic toxic substances acting on the endocrine system (endocrine disruptors), many of which are routinely used in work processes. We provide a critical review of the specialized literature on work-related chem...

AIM The aim was to evaluate the effect of multiple oral administration of bisphenol A (BPA) for 28 days on seminal characteristic on mammal using Wistar rat as a model. MATERIALS AND METHODS Rats were randomly divided into five different groups having 6 male rats in each group. The doses chosen were 50, 200, and 600 mg/kg body weight for Groups III, IV and V, respectively, based on preliminar...

Based on advanced light and electron microscopy, we describe the male reproductive system and sperm development of Limodromus assimilis. The genital tract consists of pairs of uni-follicular testes, spermatic ducts with diverticula regions, seminal vesicles, accessory glands, an unpaired ejaculatory duct and an aedeagus containing an internal sac equipped with sclerotic scales. Based on their m...

Male and female reproductive systems of Stolas conspersa (Germar) (Coleoptera, Chrysomelidae, Cassidinae). The male and female reproductive systems of Stolas conspersa (Germar, 1824) are described and illustrated for the first time. The male reproductive system shows no difference from the subfamily pattern, which is a tubular well-developed median lobe; “Y”, “V” or T-shaped tegmen; reduced pyg...

Endocrine disrupting chemicals (EDCs) can interfere with normal hormonal balance and may exert adverse consequences on humans. The male reproductive system may be susceptible to the effects of such environmental toxicants. This review discusses the recent progress in scientific data mainly from epidemiology studies on the associations between EDCs and male reproductive health and our understand...

The Wnt/β-catenin signaling pathway controls several biological processes throughout development and adult life. Dysregulation of Wnt/β-catenin signaling underlies a wide range of pathologies in animals and humans, including cancer in different tissues. In this review, we provide an update of the Wnt/β-catenin signaling pathway and the possible roles of the Wnt/β-catenin signaling in the biolog...

Background: Busulfan is a chemotherapy drug that is widely used for cancer treatment. However, administration of busulfan to male patients with malignant diseases may cause temporary or permanent sterility. Therefore, research into drugs or Materials to reduce the side effects of busulfan on the male reproductive system is necessary. In the present study the protective effects of L-carnitine an...

The pesticides are one of the most potentially harmful chemicals liberated in the environment in an unplanned manner Malathion is widely used as a potent pesticide in many countries and has been shown to produce some adverse health effects. A study was conducted to asses the effects of malathion on the male reproductive system of wistar rats. The pesticide was administered to rats orally at dos...

A substantial advance in our understanding on the estrogen signaling occurred in the last decade. Estrogens interact with two receptors, ESR1 and ESR2, also known as ERalpha and ERbeta, respectively. ESR1 and ESR2 belong to the nuclear receptor family of transcription factors. In addition to the well established transcriptional effects, estrogens can mediate rapid signaling, triggered within se...

Various findings are given emphasis to Aluminium which has more and more obvious disturbance of the reproductive processes other body organs. The purpose of this review is to give a comprehensive report of the existing data on Aluminium induced male reproductive toxicity in different animal models. Along with, we also have made an attempt to present the possible mechanism related to Aluminium i...