We read with interest “3T MRI Quantification of Hippocampal Volume and Signal in Mesial Temporal Lobe Epilepsy Improves Detection of Hippocampal Sclerosis,” in which Coan et al presented convincing evidence that quantitative assessment of hippocampal volume and T2 improves detection of hippocampal sclerosis vs visual inspection. Although we agree with the principal findings of the study, we dis...

BACKGROUND Modern automated haematology instruments are capable of performing leukocyte differentials faster, cheaper and with a higher precision than the traditional 100-cell manual differential count. Thus, in human laboratories, criteria are defined for performing a manual review of the blood smear resulting in a marked reduction of manual differential counts. While common in human laborator...

Recently, St. Anthony's Medical Center Laboratory (SAMC) in St. Louis, Missouri, installed a new automated hematology analyzer, the Sysmex XE-2100. The XE-2100 has an additional differential parameter, the immature granulocyte (IG) parameter. Prior to implementation, the IG parameter was evaluated by comparison to the manual immature granulocyte count. Immature granulocytes counted manually, as...

This paper outlines the results of a driving simulator study conducted for the European CityMobil project, which was designed to investigate the effect of a highly automated driving scenario on driver behaviour. Drivers’ response to a number of ‘critical’ scenarios was compared in manual driving with that in automated driving. Drivers were in full control of the vehicle and its manoeuvres in th...

BACKGROUND Sodium fluoride (NaF) positron emission tomography combined with computer tomography (PET/CT) has shown to be more sensitive than the whole-body bone scan in the detection of skeletal uptake due to metastases in prostate cancer. We aimed to calculate a 3D index for NaF PET/CT and investigate its correlation to the bone scan index (BSI) and overall survival (OS) in a group of patients...

BACKGROUND This study evaluated 3 new automated methods, based on a combination of speckle tracking and tissue Doppler, for the analysis of strain rate (SR) and strain. Feasibility and values for peak systolic strain rate (SR s ) and end-systolic strain (S es ) were assessed. METHODS Thirty patients with myocardial infarction and 30 normal subjects were examined. Customized software with auto...

Total body (TB) dual-energy X-ray absorptiometry (DXA) can assess regional body composition, which may necessitate greater attention to patient positioning and analysis than required for whole body assessment. This report describes technical challenges experienced in performing TB DXA, explores the frequency with which autoanalysis inaccuracies occur, assesses their effect on regional body comp...

The design of Automated Highway Systems (AHS) involves the use of advancedtechnologies and automation to make the current transportation system more efficient interms of capacity, safety and pollution. The principal question is whether thesetechnologies will lead to any benefits in terms of safety, capacity and traffic flowcharacteristics as the degree of penetration in the curr...

This is a cross sectional study conducted in the National Center of Public Health Laboratories (NCPHL) of Aden – Yemen, during October-December 2011, with an overall aim to compare the results of platelet count by the automated versus the manual methods. Study included 190 random samples, examined with confirmatory platelet estimate done by the stained thin blood film. The mean platelets count ...

BACKGROUND Lateral turning of critical care patients receiving mechanical ventilation can adversely affect hemodynamic status. OBJECTIVE To study hemodynamic responses to lateral turning. METHOD A time-series design with automated signal processing and ensemble averaging was used to evaluate changes in heart rate, mean arterial pressure, and pulse pressure due to lateral turning in 13 adult...