Mycoplasma hyopneumoniae is the causative agent of porcine enzootic pneumonia, a chronic respiratory disease, causing significant economic losses. Results from 2015?2016 MycoPath pan-European antimicrobial susceptibility monitoring survey M. are presented. In total, 147 isolates Belgium, France, Germany, Great Britain, Hungary, Italy, and Spain were tested. One isolate per farm was retained pig...

ANTIBIOTICS Fluoroquinolones The fluoroquinolone class of antibiotics work via inhibition of DNA gyrase (topoisomerase II). Resistance is mediated through chromosomal mutations in DNA gyrase which confers cross-resistance to other FQs. FQs distribute well to tissues and intracellularly. Elimination is via the kidney, and these drugs are often highly effective for treating resistant UTIs. The sp...

ANTIBIOTICS Fluoroquinolones The fluoroquinolone class of antibiotics work via inhibition of DNA gyrase (topoisomerase II). Resistance is mediated through chromosomal mutations in DNA gyrase which confers cross-resistance to other FQs. FQs distribute well to tissues and intracellularly. Elimination is via the kidney, and these drugs are often highly effective for treating resistant UTIs. The sp...

Two cases of granulomatous colitis in two French bulldogs were found to be unresponsive to fluoroquinolones. The granulomatous colitis diagnosis was made on the basis of PAS-positive histiocytes in the lamina propria of the colonic mucosa in biopsy samples taken at colonoscopy. Remission of granulomatous colitis has been reported using fluoroquinolones leading to the idea that invasive Escheric...

BACKGROUND Mycoplasma bovis is a worldwide pathogen, causative agent of pneumonia, mastitis, arthritis, and a variety of other symptoms in cattle. The economic losses due to mycoplasma pneumonia could be reduced by antibiotic treatment. The aim of the present study was to determine the in vitro susceptibility of M. bovis strains isolated from cattle in Hungary to eleven antibiotics. RESULTS M...

In this work the presence of different pharmaceuticals at Doñana National Park (Spain) and their main entry sources (input source or points) have been stated over 2011–2016 years period. Twenty-three selected (corresponding to eight therapeutic families) were evaluated in crayfish water samples from (six sampling points order cover possible pollution into surrounding Park). The multiresidue det...