نتایج جستجو برای: mas receptor

تعداد نتایج: 608237  

2010
Jennifer C. Sullivan Kanchan Bhatia Tatsuo Yamamoto Ahmed A. Elmarakby

Females are less sensitive to the hypertensive effects of angiotensin II compared with males, although the molecular mechanisms responsible are unknown. We hypothesize that differential activation of angiotensin II, angiotensin (1-7), angiotensin II type 1, angiotensin II type 2, and mas levels in the renal cortex of male and female spontaneously hypertensive rats contribute to sex differences ...

2017
Ji Soo Choi Dahye Yoon Ja Seung Koo Siwon Kim Vivian Youngjean Park Eun-Kyung Kim Suhkmann Kim Min Jung Kim

Estrogen receptor (ER)-positive breast cancers overall have a good prognosis, however, some patients suffer relapses and do not respond to endocrine therapy. The purpose of this study was to determine whether there are any correlations between high-resolution magic angle spinning (HR-MAS) magnetic resonance spectroscopy (MRS) metabolic profiles of core needle biopsy (CNB) specimens and the mole...

Mohammad Heidari, Seyed Ali Hosseini, Shahram Abootalebi,

Objectives: There are some controversies about the value of modified Ashworth Scale (MAS) for assessing spasticity. The goal of this study was to investigate if there is any correlation between scores obtained from MAS for wrist spasticity and electrophysiological recordings as the objective measure of spasticity. Methods: In this cross-sectional study, 34 stroke patients were employed. Wris...

Journal: :Hypertension 2010
Jennifer C Sullivan Kanchan Bhatia Tatsuo Yamamoto Ahmed A Elmarakby

Females are less sensitive to the hypertensive effects of angiotensin II compared with males, although the molecular mechanisms responsible are unknown. We hypothesize that differential activation of angiotensin II, angiotensin (1-7), angiotensin II type 1, angiotensin II type 2, and mas levels in the renal cortex of male and female spontaneously hypertensive rats contribute to sex differences ...

2012
Ying Han Hai-Jian Sun Peng Li Qing Gao Ye-bo Zhou Feng Zhang Xing-Ya Gao Guo-Qing Zhu

BACKGROUND Excessive sympathetic activity contributes to the pathogenesis and progression of hypertension. Enhanced cardiac sympathetic afferent reflex (CSAR) is involved in sympathetic activation. This study was designed to determine the roles of angiotensin (Ang)-(1-7) in paraventricular nucleus (PVN) in modulating sympathetic activity and CSAR and its signal pathway in renovascular hypertens...

2017
D S Skiba R Nosalski T P Mikolajczyk M Siedlinski F J Rios A C Montezano J Jawien R Olszanecki R Korbut M Czesnikiewicz‐Guzik R M Touyz T J Guzik

BACKGROUND AND PURPOSE Inflammation plays a key role in atherosclerosis. The protective role of angiotensin 1-7 (Ang-(1-7)) in vascular pathologies suggested the therapeutic use of low MW, non-peptide Ang-(1-7) mimetics, such as AVE0991. The mechanisms underlying the vaso-protective effects of AVE0991, a Mas receptor agonist, remain to be explored. EXPERIMENTAL APPROACH We investigated the ef...

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