A woman of 27 weighing 60 kg was submitted to surgery for Fallot's tetralogy. She had been an invalid all her life and was unable to walk more than a few steps. At operation dilatation of the pulmonary valve and punch excision of an infundibular stenosis was performed via the left pulmonary artery. This operation was uneventful apart from some considerable blood loss both from the pulmonary art...

Hemorrhage remains a leading cause of morbidity and death in both civilian and military trauma. Restoration of effective end-organ perfusion by stopping hemorrhage and restoring intravascular volume in such a way as to minimize acidosis, hypothermia, and coagulopathy, almost always requires the use of blood and/or blood-component therapy. The best method to manage life-threatening hemorrhage is...

background and objective: patients with thalassemia major have an abnormality in hemoglobin synthesis and ineffective hematopoiesis and for this reason with respect to disease severity should receive one or more fresh blood unit every 15-30 days. since transfusion of blood products has been known as one of the routes of hiv infection, therefore, this study was conducted to evaluate the prevalen...

conclusions: hydroxyurea can be safely used in some transfusion-dependent β-thalassemia patients to decrease their transfusion needs. background: β-thalassemia is an inherited hemoglobin disorder caused by defective synthesis of ß-globin chains. hemoglobin (hb) f induction is a possible therapeutic approach which can partially compensate for α and non-α globin chains imbalance. objectives: we a...

transfusion of blood and its components/derivatives is a life saving medical intervention. however, this life saving procedure depends mainly on the availability of sufficient blood and its components in national health sector. therefore the overall safety of transfusion medicines including the safety of blood and its available components and the appropriate use of these components would direct...

BACKGROUND The contribution of preoperative embolization in reducing intraoperative blood loss and its clinical importance are unclear. So, we aimed to compare the perioperative clinical outcomes based on whether preoperative embolization was performed and assess the role and safety of preoperative embolization in metastatic spinal cord compression (MSCC) patients. METHODS We enrolled 52 pati...

MJ Desborough,1 academic clinical fellow in haematology and transfusion medicine; SJ Stanworth,1 consultant haematologist and senior clinical lecturer in blood transfusion medicine; NS Curry,2 consultant haematologist in haemostasis and thrombosis 1NHS Blood and Transplant, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Headington, Oxford, UK; 2Oxford Haemophilia and Thombosis ...