1 Thyroid hormones (THs) are essential for proper brain development in mammals. TH insufficiency 2 during early development causes structural and functional abnormalities in brain leading to cognitive 3 dysfunction. The specific effects of developmental hypothyroidism on attention have not been well 4 characterized in animal models. The present study was conducted to characterize the effects of...

Maternal hypothyroidism has previously been shown to increase risk for neonatal intensive care treatment, but otherwise the association between thyroid diseases and neonatal morbidity is understudied. The Consortium on Safe Labor, a retrospective cohort (2002-2008), included 223,512 singleton deliveries of which 0.2% had hyperthyroidism, 1.4% primary and 0.1% iatrogenic hypothyroidism, and 1.3%...

The pathogenesis of congenital hypothyroidism due to thyroid dysgenesis is still unknown. A point mutation in the TSH receptor (TSHR) of the hypothyroid hyt/hyt mouse invoked the TSHR as a candidate gene for congenital hypothyroidism. Therefore, we screened for mutations in the TSHR gene in patients with congenital hypothyroidism and hypoplasia of the gland. In one girl detected in neonatal scr...

background primary congenital hypothyroidism (ch) is the most common treatable cause of mental retardation and can be classified into permanent and transient types. the purpose of this study was to determine the prevalence of permanent and transient congenital hypothyroidism (ch) in hamadan, west province of iran. methods the study population included all cases with primary congenital hypothyro...

Introduction: Hypothyroidism is a common endocrine disorder occurring in pregnancy. Maternal and fetal complications are present these patients. Timely identification treatment help the prevention of complications. The aim this study was to find out prevalence hypothyroidism among pregnant women attending Outpatient Department Obstetrics tertiary care centre. Methods: A descriptive cross-sectio...

Aim. To investigate obstetric features of pregnant women with thyroid disorders and thyroid function tests of their newborn infants. Methods. Women with hypothyroidism and having anti-thyroglobulin (ATG) and anti-thyroid peroxidase (anti-TPO) antibodies were assigned as group I, women with hypothyroidism who did not have autoantibodies were assigned as group II, and women without thyroid proble...