background and objectives : the main cause of serious nosocomial infections is a gram-negative pathogen known as pseudomonas aeruginosa (p. aeruginosa). carbapenems are widely used as an appropriate treatment for these infections, however resistance to these agents has been observed and is increasing. metallo beta-lactamase (mbls) enzyme is one of the main causes of resistance to carbapenem. in...

background and objectives: cystic fibrosis (cf) is an autosomal recessive genetic disease.  infections in these patients gene.are  mostly  caused  by  three  bacteria:  staphylococcus  aureus ,  haemophilus  influenza and  particularly  pseudomonas aeruginosa .  carbapenems including antibiotics are used to combat infections with pseudomonas aeruginosa . in recent years, carbapenems resistant s...

The Pseudomonas aeruginosa-containing wastewater released by hospitals is treated by wastewater treatment plants (WWTPs), generating sludge, which is used as a fertilizer, and effluent, which is discharged into rivers. We evaluated the risk of dissemination of antibiotic-resistant P. aeruginosa (AR-PA) from the hospital to the environment via the wastewater network. Over a 10-week period, we sa...

INTRODUCTION/AIM Pseudomonas aeruginosa (P. aeruginosa) is the most common cause of wound infections, following the disruption of the skin or mucous membranes integrity. The aim of this study was to analyze of the presence P. aeruginosa in wound swabs, antibiotics susceptibility testing, determination of the minimum inhibitory concentrations (MICs) of antibiotics, testing of the metallo-β-lacta...

BACKGROUND One of the major clinical problems regarding Pseudomonas aeruginosa is attributed to metallo-beta-lactamases (MBL). This group of enzymes is a subset of beta lactamases which belong to group B of Ambler classification and cause hydrolysis of carbapenems. Based on epidemiological studies conducted worldwide, it is proved that prevalence of genes coding MBLs in P. aeruginosa species ar...

All (236) Pseudomonas aeruginosa isolates resistant to imipenem and/or meropenem collected during a multicenter (127-hospital) study in Spain were analyzed. Carbapenem-resistant isolates were found to be more frequently resistant to all beta-lactams and non-beta-lactam antibiotics than carbapenem-susceptible isolates (P < 0.001), and up to 46% of the carbapenem-resistant isolates met the criter...