Main control room (MCR) is an important site of the nuclear power plant (NPP), and the environmental condition in MCR shall be benefit to operators performing their task effectively and comfortably. With the development of HFE (human factor engineering), there is more attention to environment design of MCR. the MCR environment designmainly include noise reduction, illumination, air condition, i...

Since our first identification of plasmid-mediated colistin resistance gene mcr-1 in 2015 (Liu et al., 2016), it has been described in human clinics, domestic animals, foods, and the environment worldwide (Schwarz & Johnson, 2016). Although it is still rare, the emergence of mcr-1 in wild animals is of great concern. We summarized two previous reports on mcr-1 in wild birds from Lithuania and A...

We describe a hospital-based outbreak caused by multidrug-resistant, Klebsiella pneumoniae carbapenemase 3-producing, mcr-1-positive K. pneumoniae sequence type 45 in Portugal. mcr-1 was located in an IncX4 plasmid. Our data highlight the urgent need for systematic surveillance of mcr-1 to support adequate therapeutic choices in the nosocomial setting.

amyotrophic lateral sclerosis (als), the most common form of motor neuron disease, is a progressive and devastating disease involving both lower and upper motor neurons, typically following a relentless progression towards death. therefore, all efforts must be made by the clinician to exclude alternative and more treatable entities. als with laboratory abnormalities of uncertain significance is...

In this paper, we propose a delayed multiple copy retransmission (D-MCR) scheme. By using Markovian analytic method we present the performance evaluation of the D-MCR scheme in correlated fading channels. Both effective throughput and number of retransmissions are derived. The analytic results show that the D-MCR scheme can improve the performance greatly, especially in slow fading channels.

abstract   background: amyotrophic lateral sclerosis (als) is a progressive neurological disorder with high mortality and morbidity. some risk factors have been implicated for als such as exposure to high magnetic fields, and trace elements like selenium, cadmium and lead. afew studies have been carried out throughout the world to evaluate the prevalence of als among veterans. this study was ai...

The spread of mcr-1 in the United States remains poorly defined. mcr-1-producing Escherichia coli that also carried blaSHV-12 was detected in a hospitalized patient. No additional cases were identified during screening of 801 Gram-negative isolates. Genomic sequencing identified an IncX4 mcr-1- harboring plasmid and ST117 clonal background associated with avian pathogenic E coli.

Objective(s): Amyotrophic lateral sclerosis (ALS), a fatal progressive neurodegenerative disorder, is the most common motor neuron disease in European populations. Approximately 10% of ALS cases are familial (FALS) and the other patients are considered as sporadic ALS (SALS). Among many ALS causing genes that have been identified, mutations in SOD1 and C9orf72 are the most common genetic causes...

The emergence of a transferable colistin resistance gene (mcr-1) is of global concern. The insertion sequence ISApl1 is a key component in the mobilization of this gene, but its role remains poorly understood. Six Escherichia coli isolates were cultured from the same patient over the course of 1 month in Germany and the United States after a brief hospitalization in Bahrain for an unconnected i...