introduction: intensive care unit is one of the most stressful wards for patients and it is estimated that 30 to70 percent of patients experience severe physiologic stress during admission. some of the physiologic responses to stress include increase in metabolic rate with consequent increase in body temperature, increase in cardiac output and contraction power and subsequently increase in bloo...

We investigated the role of insulin in salt-sensitive hypertension in Dahl salt-sensitive and salt-resistant rats. The rats were kept in metabolic cages, and sodium intake and urinary sodium excretion were measured. In salt-sensitive rats receiving a 0.3% NaCl diet, sodium retention was significantly greater at weeks 1 and 2 in rats that received an insulin infusion than in those receiving a sa...

Oscillations in mean arterial blood pressure (MABP) with periods near 1.5 hours were observed in conscious male dogs with pressure transducers implanted in their aortas. Cardiac output (CO) was measured with an electromagnetic flow probe implanted about the ascending aorta, and total peripheral resistance (TPR) was calculated as the ratio of MABP to CO. Heart rate (HR) was measured with a cardi...

introduction: the effect of severe soft tissue injury on the severity of hemorrhagic shock is still unknown. therefore, the present study was aimed to determine hemodynamic and metabolic changes in traumatic/hemorrhagic shock in an animal model. methods: forty male rats were randomly divided into 4 equal groups including sham, hemorrhagic shock, soft tissue injury, and hemorrhagic shock + soft ...

This study was performed to compare continuous Finapres (FIN) and intrabrachial (IAP) blood pressure in healthy elderly volunteers. Fifteen elderly subjects (age 71 to 83) without cardiovascular disease and an intraarterial mean (range) systolic and diastolic blood pressure of 162 (122 to 195) and 73 (62 to 88) mm Hg, respectively, participated in the study. A 10-min head-up tilt, 10 min active...

BACKGROUND The aim of the present study was to determine the respective influences of local pulse pressure and mean blood pressure on arterial remodeling in humans at 2 arterial sites: a central, predominantly elastic artery (the common carotid artery) and a peripheral muscular artery (the radial artery). METHODS AND RESULTS Forty-three healthy subjects and 124 never-treated hypertensive pati...

This case series of 27 patients with large stroke challenges the current state of the art guiding hemodynamic management by blood pressure levels. The results show that assumed correlations of blood pressure, cardiac output, and systemic vascular resistance do not exist. Therefore, hemodynamic therapy may better be guided by cardiac output.