Alternative crystal structures are possible for all lipids and each different crystal structure is called a polymorphic form. Inter-conversion between polymorphisms would imply the possibility of leaning crystal formation toward the most effective polymorphism for adipocyte destruction. Food industry has been tempering lipids for decades. Tempering technology applied to lipocryolysis gave birth...

BACKGROUND In a Caucasian population, the prevalence and incidence of hypertension, renal function and large artery stiffness were significantly correlated with polymorphisms in the genes encoding the angiotensin-converting enzyme (ACE I/D), aldosterone synthase (-C344T) and the cytoskeleton protein alpha-adducin (Gly460Trp). OBJECTIVE This study investigated intima-media thickening, a precur...

OBJECTIVE The purpose of this report is to describe an automatic real-time system for evaluation of the carotid intima-media thickness (CIMT) characterized by 3 main features: minimal interobserver and intraobserver variability, real-time capabilities, and great robustness against noise. METHODS One hundred fifty carotid B-mode ultrasound images were used to validate the system. Two skilled o...

Objective(s): Atherosclerosis is an important risk factor for coronary heart disease. Neuropeptide Y (NPY) and its receptors, located in peripheral tissue such as white adipose tissue, have been linked to obesity and fat storage. The role of NPY in atherosclerosis has not yet been fully studied, so this study was conducted to further investigate the effect of BIIE 0246, an NPY receptor antagoni...

Objective: A magnesium deficiency is known to be involved in many abnormalities in the post-menopausal women. Previous studies proposed that magnesium (Mg) might prevent atherosclerosis. In this study the efficacy of serum magnesium level and its relation with carotid intima media thickness (CIMT) in post-menopausal women was evaluated. Methods: Eighty Iranian Postmenopausal women were included...

BACKGROUND AND OBJECTIVES The role of reversibility of nontraditional risk factors, like inflammation and CKD-mineral bone disorder, in the reduction of cardiovascular risk after renal transplantation is still scarcely defined. DESIGN, SETTING, PARTICIPANTS, AND MEASUREMENTS The longitudinal relationship between C-reactive protein, CKD-mineral bone disorder biomarkers, and intima media thickn...

laboratories that have sought to use the anatomical and pathological rationale that I have suggested above should drive the carotid intima–media thickness protocol, I believe the use of the composite measure would be strongly confirmed. Finally, when considering what segments should be studied in evaluating the effectiveness of a drug in retarding the progression of carotid intima–media thickne...

The present study investigates effects of surrounding tissues and non-uniform wall thickness on the biomechanics of the thoracic aorta. We construct two idealised computational models exemplifying the importance of surrounding tissues and non-uniform wall thickness, namely the uniform-thickness model and the histology image-based model. While the former neglects a connective tissue layer surrou...

BACKGROUND Restriction in fetal growth is associated with cardiovascular disease in adulthood. It is unclear whether abnormal intrauterine growth influences arterial morphology during the fetal or neonatal stage. The objective was to study the regional arterial morphology with respect to gestational age and abnormal fetal body size. METHODS AND RESULTS We studied body anthropometrics and arte...

BACKGROUND Cerebral emboli resulting from atherosclerosis at the carotid bifurcation is a major cause of ischemic stroke. A convenient and prompt evaluation is necessary for secondary prevention and treatment. METHODS In this study, one hundred and thirty eight patients with cerebral ischemic events were enrolled; 100 patients with nonischemic cerebral diseases were enrolled as controls. Noni...