The need for new drugs to treat microbial infections is pressing. The great progress made in the middle part of the twentieth Century was followed by a period of relative inactivity as the medical needs relating to infectious disease in the wealthier nations receded. Growing realisation that anti-infectives are needed in many parts of the world, to treat neglected diseases as well as to combat ...

Zenovia Moldovan and Irinel Adriana Badea Department of Analytical Chemistry, Faculty of Chemistry, University of Bucharest, 92-96, Sos. Panduri, Bucharest-5, 050663, Romania Andrei A. Bunaciu CROMATEC_PLUS SRL, Analytical Research Department, 18 Sos. Cotroceni, Bucharest 6, 060114, Romania Hassan Y. Aboul-Enein* Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industr...

Assem Barakat 1,3,*, Saied M. Soliman 2,3,*, Hazem A. Ghabbour 4,5, M. Ali 1, Abdullah Mohammed Al-Majid 1, Mohammad Shahidul Islam 1 and Ayman A. Ghfar 1 1 Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia; [email protected] (M.A.); [email protected] (A.M.A.-M.); [email protected] (M.S.I.); [email protected] (A.A.G.) 2 Departm...

Coumarins are one of the most important classes of heterocycles that occupies prime position in synthetic and pharmaceutical chemistry due to their diverse applications. Broad spectrum of biological activity and their utility as useful synthons, coumarins have attracted researchers to work on this moiety, which is instrumental in the development of coumarin chemistry. This review article provid...

Address: 1Institute of Experimental and Clinical Pharmacology, Medical University of Graz, 8010 Graz, Austria , 2Ernest Gallo Clinic and Research Center, University of California San Francisco, CA 94608, USA, 3Leiden/Amsterdam Center for Drug Research (LACDR), Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, 1081 HV Amsterdam, The Netherlands and 4Department of Der...