There is a relative lack of information on the course of corticohypoglossal projections in the human brain stem, 2 especially in the medulla. Using transcranial magnetic stimulation and magnetic resonance imaging (MRI) in 11 patients with ischaemic lesions at different brain stem levels, Urban et al showed that pontine lesions at the ventral paramedian base close to the midline affected the con...

Background. Trigeminal neuralgia secondary to medulla oblongata compression by dolichoectasia of the vertebral artery is rare. Case report. A 60-year-old patient with trigeminal a dolichoectatic presented. There was remarkable improvement in pain after treatment Gabapentine. Conclusions. Direct involvement nerve usual mechanism neuralgia. However, might be an important non-recognized cases doli...

As determined by serial histologic study, the leukocyte component of the acute inflammatory response to thermal injury in the medulla of the kidney of rabbits was markedly delayed and diminished in intensity when compared with the response of the cortex. Similar differences in granulocyte mobilization between cortex and medulla were seen following the inoculation of bacteria. Hydronephrosis pro...

In the developing Drosophila optic lobe, eyeless, apterous and distal-less, three genes that encode transcription factors with important functions during development, are expressed in broad subsets of medulla neurons. Medulla cortex cells follow two patterns of cell movements to acquire their final position: first, neurons are arranged in columns below each neuroblast. Then, during pupation, th...

We report 10 cases of cerebellar infarction in the territory of the medial branch of the posterior inferior cerebellar artery (mPICA). Axial sections on MRI through the middle of the medulla and the cerebellum showed the infarction as a triangular area with a dorsal base and a ventral apex directed towards the fourth ventricle. The infarct also involved the lateral and dorsal medulla when the m...

Beta-endorphin (B-END) like imnunoreactivity (i.r.) levels were measured by radioimnunoassay in the medulla oblongata of developing rats on postnatal ages Pl-P42 at 7 day intervals, and in adult rats. Fran Pl to P42, B-END i.r. increased fran 77.0 + 1.3 fm to 900.0 + 21.6 fm per medulla region (Mean + S.E.M.) . Adult levels of B-END i.r. were F52.0 + 17.0 fm per medulla region, When B-END i.r. ...

BACKGROUND In response to high salt intake, transcription factor hypoxia-inducible factor (HIF) 1α activates many antihypertensive genes, such as heme oxygenase 1 (HO-1) 1 and cyclooxygenase 2 (COX-2) in the renal medulla, which is an important molecular adaptation to promote extra sodium excretion. We recently showed that high salt inhibited the expression of HIF prolyl-hydroxylase 2 (PHD2), a...

The post-translational processing of pro-opiomelanocortin (POMC) in brain remains controversial. Classically, there was thought to be a single cell group in the arcuate nucleus with long projections through limbic structures. More recently, a second cell group was discovered in the caudal medulla. This study addresses the question of POMC processing in this region. Steady-state analysis of acid...

We have developed a highly detailed mathematical model of solute transport in the renal medulla of the rat kidney to study the impact of the structured organization of nephrons and vessels revealed in anatomic studies. The model represents the arrangement of tubules around a vascular bundle in the outer medulla and around a collecting duct cluster in the upper inner medulla. Model simulations y...

BACKGROUND AND PURPOSE Menière disease and idiopathic sudden sensorineural hearing loss can have overlapping clinical presentation and may have similar pathophysiology. Prior studies using postcontrast 3D-FLAIR MR imaging suggest abnormal blood-labyrinth barrier permeability in both conditions, but the 2 diseases have not been directly compared by using the same imaging techniques. We hypothesi...