نتایج جستجو برای: megaloblastic anemia

تعداد نتایج: 56499  

Journal: :Blood 1960
T W SHEEHY M E RUBINI R BACO-DAPENA E PEREZ-SANTIAGO

O NE OF the primary nlanifestations of tile clinical entity tropical sprue is a severe megaloblastic anemia. Although detailed descriptive information is available on tile blood and bone marrow morphology of this anenlia, its pathogenesis remains obscure.4’ The purpose of this report is to describe the quantitative aspects of red! cell production and dlestruction in this anemia. Our observation...

Journal: :Blood 2009
Michael L Chen T Daniel Logan Maryann L Hochberg Suresh G Shelat Xiang Yu Gregory E Wilding Wei Tan Gregory C Kujoth Tomas A Prolla Mary A Selak Mondira Kundu Martin Carroll James E Thompson

Recent reports describe hematopoietic abnormalities in mice with targeted instability of the mitochondrial genome. However, these abnormalities have not been fully described. We demonstrate that mutant animals develop an age-dependent, macrocytic anemia with abnormal erythroid maturation and megaloblastic changes, as well as profound defects in lymphopoiesis. Mice die of severe fatal anemia at ...

Journal: :Irish journal of medical science 1961
M L WILLOUGHBY M A PEARS A A SHARP M J SHIELDS

2011
Claus Zehetner Nikolaos E. Bechrakis

BACKGROUND To report a case of severe vitamin B(12) deficiency anemia presenting with white centered retinal hemorrhages. METHODS Interventional case report. RESULTS A 40-year-old man, general practitioner himself, presented with a 1-day history of diminished left visual acuity and a drop-shaped central scotoma. The corrected visual acuities were 20/20, OD and 20/100, OS. Ophthalmic examina...

2015
Gunvanti B. Rathod Mobeen Alwani Hardi Patel Annie Jain

Introduction: Pancytopenia is condition in which there is reduction of all the 3 peripheral blood lineage and must be suspected on clinical grounds when a patient presents with unexplained pallor. Careful examination of a blood film is important if reason for the pancytopenia is not apparent from the clinical history. If this does not reveal the cause, bone marrow aspiration and trephine may be...

2013
Kirpal Das Makheja Bharat Kumar Maheshwari Shafique Arain Suneel Kumar Sangeeta Kumari Vikash

OBJECTIVE The objective of this study was to determine the frequency of common causes leading to Pancytopenia in patients presenting to tertiary care hospital at Karachi. METHODS A total of 62 patients with the diagnosis of Pancytopenia of more than one week duration were enrolled in the study. All patients underwent a detailed medical history and full physical examination followed by blood s...

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