نتایج جستجو برای: meglumine antimoniate
تعداد نتایج: 930 فیلتر نتایج به سال:
Canine leishmaniosis (CanL) due to Leishmania infantum is a life threatening zoonotic disease with a wide distribution in four continents and importance also in non-endemic regions. The purpose of this report is to present a consensus of opinions on the diagnosis, treatment, prognosis and prevention of CanL in order to standardize the management of this infection. CanL is a disease in which inf...
Toxicity and drug resistance against pentavalent antimonials, medications of choice in treatment of leishmaniasis for more than 5 decades, have become important subjects globally. This study was a randomized, open labeled trial that was designed to determine efficacy and safety of IMOD as a novel herbal immunomodulator drug for treatment of canine visceral leishmaniasis (CVL). Twenty healthy mo...
Meglumine antimoniate (MA) is a pentavalent antimony (SbV) drug recommended for the treatment of leishmaniasis. It known that trivalent (SbIII) present as residue in MA contributes to side effects. In this article, multivariate optimization was used synthesis order obtain with low levels SbIII. Four variables (source antimony, temperature, water volume and pH) were preliminarily evaluated by 24...
Canine gastrointestinal infection by Leishmania presenting large bowel involvement has been reported to date. This case series describes two dogs suffering from severe chronic small bowel diarrhea. Duodenal biopsies demonstrated granulomatous infiltration with intracytoplasmatic corpuscles of Leishmania amastigotes. Furthermore one of the dogs was diagnosed with protein-losing enteropathy (PLE)...
While relapses following clinical cure of American cutaneous leishmaniasis are frequent, no test has been described until now to predict such relapses. A cohort of 318 American cutaneous leishmaniasis patients was followed up for two years after treatment with meglumine antimoniate, during which time 32 relapses occurred, 30 in the first year and two in the second (accumulated risk: 10.5%). No ...
Leishmaniasis is a parasitic disease caused by Leishmania species and is classified into three forms; cutaneous, mucocutaneous, and visceral. The eyelid is a rare site involved by leishmaniasis and only makes up 2.5% of cases with cutaneous leishmaniasis (CL). Although CL can affect both upper and lower lids on either their outer or inner aspects, the lateral canthus is most often affected. The...
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