The recent melamine crisis in China has pointed out a serious deficiency in current food control systems, namely, they specifically focus on selected known compounds. This targeted approach allowed the presence of melamine in milk products to be overlooked for a considerable time. To avoid such crises in the future, we propose that nontargeted screening methods need to be developed and applied....

Changes of neural oscillations at a variety of physiological rhythms are effectively associated with cognitive performance. The present study investigated whether the directional indices of neural information flow (NIF) could be used to symbolize the synaptic plasticity impairment in hippocampal CA3-CA1 network in a rat model of melamine. Male Wistar rats were employed while melamine was admini...

OBJECTIVE To investigate the renal outcomes of children after exposure to low dose melamine in Hong Kong. DESIGN Cross sectional study. SETTING Special assessment centres, Hong Kong. PARTICIPANTS 3170 children (1422 girls and 1748 boys) aged 12 years or less referred from territory-wide primary care clinics after daily consumption for one month or more of milk products tainted with melami...

Melamine is an organic nitrogenous compound widely used as an industrial chemical, and it has been recently reported by us that melamine has a toxic effect on the female reproductive system in mice, and renders females subfertile; the molecular basis, however, has not been adequately assessed. In the present study, we explore the underlying mechanism regarding how melamine compromises fertility...

Multivariate calibration (MVC) and near-infrared (NIR) spectroscopy have demonstrated potential for rapid analysis of melamine in various dairy products. However, the practical application of ordinary MVC can be largely restricted because the prediction of a new sample from an uncalibrated batch would be subject to a significant bias due to matrix effect. In this study, the feasibility of using...

      The photocatalytic degradation of two anionic azo dyes Acid Red88 (AR 88) and Acid Orange 7 (AO7) was investigated in aqueous solution using a TiO2-containing hydrogel and UV light. The pH-sensitive hydrogel poly (styrene-alt-maleic anhydride) (PSMA), was synthesized and crosslinked in the presence of melamine and TiO2 nanoparticles which results in entrapment of TiO...

A liquid chromatography triple quadrupole tandem mass spectrometry (LC-MS/MS) method for residues of cyanuric acid (CYA) and melamine (MEL) developed by the Center for Veterinary Medicine (CVM) has been adapted for use with infant formula. This method consists of an initial extraction with 2.5% aqueous formic acid, followed by a series of filtration, centrifugation, and dilution steps. Both com...

The objective of this project was to use sucrose as a partial substitute for melamine in the synthesis of sucrose–melamine-formaldehyde (SMF) resin. The SMF was synthesized in a base condition. The wet bonding strength, shelf life, and formaldehyde emission of the SMF resin were determined. Fourier transform infrared spectroscopy (FT-IR) and mass spectroscopy (MS) were employed to analyze the c...

A simple, precise, accurate, and validated reverse-phase HPLC method was developed for the determination of melamine in milk (pasteurized and UHT milk) and dairy products (powdered infant formula, fruit yogurt, soft cheese, and milk powder). Following extraction with acetonitrile:water (50:50, vol/vol), samples were purified by filter (0.45 μm), separated on a Nucleosil C8 column (4.6 mm × 250 ...