Background and aim: It seems that melanocytic nevi, freckle and lentigo are more common in women with melasma, and a common genetic background may exist. In this study the prevalence and number of lentigo, freckle and melanocytic nevus were compared in women with and without melasma.Materials and methods: In a case-control study, 120 women with melasma (case group) and ...

Melasma is a common, chronic skin condition of hyperpigmentation involving the appearance symmetric and irregular light brown macules patches, mainly on sun exposed head neck. Though pathogenesis not fully understood, hyperfunctional melanocytes are known to deposit excess melanin in epidermis dermis. Known risk factors or triggers include genetic influence, hormonal ultraviolet radiation. Due ...

Introduction Melasma and postinflammatory hyperpigmentation (PIH) are conditions commonly encountered by dermatologists, they often distressing to patients. While PIH can improve with time once the inflammatory process is controlled, melasma a condition that requires prolonged treatment maintenance. There numerous options, ranging from UV protection topical therapies (such as hydroquinone), mor...

Background: Melasma is a common pigmentary disorder which presents with brown coloured macules that occurs around the sun-exposed areas of skin, particularly on face. Many treatment modalities are present but often it resistant to treatment. The aim our study was compare therapeutic efficacy and safety tranexamic acid administered by oral topical route in patients melasma. Methods: Our prospect...

Treatment of melasma, a hyperpigmentation disorder, remains a challenge. The primary objective of two 8-week, multicenter, randomized, investigator-blind studies was to compare the efficacy and safety of a hydrophilic cream formulation containing tretinoin 0.05%, hydroquinone 4.0%, and fluocinolone acetonide 0.01% (RA+HQ+FA) with the dual-combination agents tretinoin plus hydroquinone (RA+HQ), ...

Background: Melasma is a common acquired skin disorder that presents as bilateral, blotchy, brownish facial pigmentation due to dysfunction in melanogenesis. It most people who tans easily or have naturally brown (Fitzpatrick’s phototypes III, IV). Although several treatments are currently used, it remains great challenge. Aim: This study aims compare the efficacy of intradermal injection trane...

Introduction: Melasma is a very common and difficult to treat hypermelanosis because it usually responds poorly therapies, negatively affecting the quality of life patients. Objective: know analyze scientific evidence related treatment patients with facial melasma treated niacinamide. Method: literature review was performed based on data search in BIREME, PubMed, SciELO ScienceDirect. Articles ...

Melasma is a challenging pigmentation disorder to treat, and although low-fluence 1064 nm picosecond ND-YAG lasers have shown potential for treating benign pigmented disorders, data on the use of this laser melasma treatment are currently insufficient. In prospective split-face study, twenty-four patients with face were enrolled randomly assigned receive one side either or PTP mode Q-switched l...

: Melasma is a common dermatosis, presenting as ill-defined light to dark brown pigmentation of photo-exposed areas, most commonly the face. Its exact prevalence unknown, but it commoner in intermediate skin phototypes and women reproductive age. treatment monitoring have significance due its chronic recalcitrant history psychosocial impact. Various indices tools like melasma area severity Inde...