BACKGROUND Melasma is an acquired disorder of hypermelanosis of great psychosocial concern. The treatments with various conventional therapies are often unsatisfactory. Lasers and light sources have been used to treat pigmented lesions, but in Asian skin with higher melanin content, such treatments may be challenging. OBJECTIVES To determine the effectiveness of treating melasma with a combin...

Melasma is a common disorder affecting a significant percentage of the population, particularly those with skin of color. Therapy with hydroquinone, a depigmenting agent, as a single agent or in combination with other agents has been used with variable success. A triple-combination (TC) cream combining hydroquinone 4% with tretinoin 0.05% and fluocinolone acetonide 0.01% was developed for the t...

OBJECTIVE To compare the efficacy and safety of Jessner's solution with 30% salicylic acid as superficial chemical peeling agents in treating epidermal melasma in Asian skin. STUDY DESIGN Double blind, randomized, interventional comparative study. PLACE AND DURATION OF STUDY Department of Dermatology, Combined Military Hospital, Malir Cantt, Karachi, from January to December 2004. PATIENT...

Fractional resurfacing may be used in the management of melasma, striae/stretch marks, acne scars, pearly penile papule, syringoma, burn scar, verrucous epidermal naevus and skin tightening. In 20-30% of the patients with melasma, fractional resurfacing may not be effective or may even cause an exacerbation. Treatment effects may also be temporary. When compared with traditional carbon dioxide ...

Melasma is a pigmentary disorder that is characterized by poorly defined, dark brown macules on sun exposed areas, such as the face, back, and arms. This hyperpigmentation condition affects millions of people worldwide, the majority of whom are women. In the United States alone, it is estimated to affect over 6 million people, including up to 40% of the US female population1. Melasma is more pr...

To evaluate the efficacy of a functional microarray of microneedles (MNs) plus topical tranexamic acid (TA) for melasma in middle-aged women in China.Thirty female subjects with melasma were enrolled in this study. The left or right side of the face was chosen randomly to be pretreated with a functional microarray of MNs, followed by topical 0.5% TA solution once per week for 12 weeks. The othe...

The demand for aesthetic and rejuvenating treatments is increasing in society, with that the orofacial harmonization increases exponentially every day. Orofacial a set of procedures performed by Dentist / Dental Surgeon, which aims at functional balance face. Steroid hormones are great importance aging due to decrease some during this process. However, poor diet including sugar consumption, cha...

Melasma (or chloasma) is a hyperpigmentation disorder predominantly affecting sun-exposed skin in women, and is often refractory to treatment. The objective was to evaluate the efficacy and safety of a new whitening formula for the treatment of chloasma. This single centre, double-blind, placebo controlled, bilateral (split-face) comparison, was conducted on 44 Chinese subjects with chloasma du...