Vyanga (Melasma) is condition of localized hypermelanosis which affect face, and continues to be challenging problem as it causes immense mental stress depression. In ayurvedic texts there lot ahara, aushadha, vihara were mentioned enhance external beauty such varnya varg told by Acharya Charak, romsanjanan etc Shushrut. Melasma can correlated with in Ayurveda. The present study was aimed evalu...

Background Melasma is a common disorder of pigmentation, characterized by symmetric brown or brown-gray patches in sun-exposed facial areas. Hydroquinone (HQ) is the most effective agent in melasma treatment; however it has some adverse events (AE) that limit its extensive use. We evaluated the clinical response of aminoacid filaggrin-based antioxidants (AFBA) in Mexican patients with centrofac...

Introduction Melasma and postinflammatory hyperpigmentation (PIH) are conditions commonly encountered by dermatologists, they often distressing to patients. While PIH can improve with time once the inflammatory process is controlled, melasma a condition that requires prolonged treatment maintenance. There numerous options, ranging from UV protection topical therapies (such as hydroquinone), mor...

Background: Melasma is a common pigmentary disorder which presents with brown coloured macules that occurs around the sun-exposed areas of skin, particularly on face. Many treatment modalities are present but often it resistant to treatment. The aim our study was compare therapeutic efficacy and safety tranexamic acid administered by oral topical route in patients melasma. Methods: Our prospect...

Treatment of melasma, a hyperpigmentation disorder, remains a challenge. The primary objective of two 8-week, multicenter, randomized, investigator-blind studies was to compare the efficacy and safety of a hydrophilic cream formulation containing tretinoin 0.05%, hydroquinone 4.0%, and fluocinolone acetonide 0.01% (RA+HQ+FA) with the dual-combination agents tretinoin plus hydroquinone (RA+HQ), ...

Background: Melasma is a common acquired skin disorder that presents as bilateral, blotchy, brownish facial pigmentation due to dysfunction in melanogenesis. It most people who tans easily or have naturally brown (Fitzpatrick’s phototypes III, IV). Although several treatments are currently used, it remains great challenge. Aim: This study aims compare the efficacy of intradermal injection trane...