BACKGROUND Adolescent girls aged 15-19 bear a disproportionate burden of negative sexual and reproductive health outcomes in low- and middle-income countries. Research from several high-income countries suggests that early age at menarche is an important determinant of sexual and reproductive health. We conducted this systematic review to better understand whether and how early menarche is asso...

background menarche is considered as a milestone in the women’s reproductive life. most existing studies on factors influencing menarcheal age had cross-sectional designs and their finding were controversial. objectives we aimed to determine some factors affecting the age at menarche in a cohort study with an average of ten-year follow-up; the study was conducted within the framework of tehran ...

Prepubertal vaginal bleeding is considered as isolated menarche when, in the absence of detectable abnormality, it is not accompanied by any evidence of sexual development. The etiology remains unclear and various hypotheses have been put forward. This is the first time that a series of ultrasound patients with prepubertal menarche whose investigation has included imaging with ultrasound has be...

BACKGROUND Earlier age of pubertal maturation in females is associated with increased risk for mental health problems in adolescence, compared with on-time or later maturation. However, most investigations of pubertal timing and mental health consider risk for individual disorders and fail to account for comorbidity. A latent-modeling approach using a large, nationally representative sample cou...

BACKGROUND Early menarche has been associated with increased risk of coronary heart disease (CHD), but most studies were relatively small and could not assess risk across a wide range of menarcheal ages; few have examined associations with other vascular diseases. We examined CHD, cerebrovascular disease, and hypertensive disease risks by age at menarche in a large prospective study of UK women...

The goal of this study is to determine the age at menarche of girls from Tanzania examined in 2005 considering their families' social and material status. For the purpose of the analysis of the age at menarche, N = 71 girls were qualified (N = 8 from Dares Salaam and N = 63 from Mafinga) out of N = 98 who took part in the anthropological study. The calendar age of the girls who qualified for th...

Cadmium exposure can cause several adverse health effects. Animal studies have also shown that cadmium exposure can affect menarche or menopause. However, data is limited in humans. We conducted a retrospective study to assess whether cadmium exposure was associated with different ages of menarche and menopause in a Chinese population. A total of 429 women living in control (n = 137) and two ca...

Little is known about the impact of age at menarche on later mortality. In a cohort of 61,319 Norwegian women interviewed in 1956-1959, the authors analyzed associations between age at menarche and all-cause mortality. A total of 36,114 women died during the 37 years of follow-up. An inverse association was found between age at menarche and the all-cause mortality rate (p < 0.001), with an appr...

Early menarche is known to be associated with diabetes, however this association remains controversial. Our study aimed to investigate the possible association between age at menarche and diabetes prevalence in post-menopausal Korean women. This study included 3,254 post-menopausal Korean women aged 50-85 years from the Korea National Health and Nutrition Examination Survey IV (KNHANES 2007-200...

BACKGROUND Although dichlorodiphenyl trichloroethane (DDT) exposure is known to affect human endocrine function, few previous studies have investigated the effects of DDT exposure on age at menarche or menstrual cycle length. METHODS A cross sectional study was conducted to study the effects of DDT exposure on age at menarche and menstrual cycle length among 466 newly married, nulliparous fem...