BACKGROUND The effect of menopausal transition on the frequency of migraine has never been the focus of a community-based study. METHODS A cross-sectional community-based survey was undertaken among Chinese women aged 40 to 54 years in Kinmen, Taiwan. Neurologists diagnosed migraine based on the 1988 International Headache Society classification criteria. Menstrual history including a past or...

BACKGROUND Magnesium plays a role in glucose and insulin homeostasis and evidence suggests that magnesium intake is associated with insulin resistance (IR). However, data is inconsistent and most studies have not adequately controlled for critical confounding factors. OBJECTIVE The study investigated the association between magnesium intake and IR in normal-weight (NW), overweight (OW) and ob...

BACKGROUND The association of obstructive sleep apnea (OSA) with glucose intolerance and the beneficial effect of lifestyle intervention have been poorly investigated in women particularly before menopausal status. The study explored 1) whether OSA is associated with impaired glucose homeostasis in obese non diabetic premenopausal and menopausal women and 2) the effects of a 3- month lifestyle ...

A historical account is presented of the development of sex hormone treatment from its beginning at the Peking Union Medical College to its present-day generalization throughout China. The general theme of this work has been to test low-dose hormone regimens. Notable successes include low-dose oral contraception and menopausal hormone treatment. In support of the latter, we present a new clinic...

Cervical sarcomatoid squamous cell carcinoma (SSCC) is an extremely rare malignancy. We report the case of a young woman with cervical SSCC who experienced peri-menopausal syndrome following treatment, and present our evaluation of the considerations relating to hormone replacement therapy (HRT) in this case. A 24-yearold Chinese woman with SSCC underwent radical hysterectomy with bilateral sal...

Recent reports of mammoplasia during selective serotonin re-uptake inhibitor (SSRI) therapy suggested that this side effect may be more common than previously reported. We examined 59 women receiving > or = 2 months treatment with an SSRI or venlafaxine for changes in breast size in relation to menopausal status, weight gain and duration of drug therapy. Serum prolactin, estradiol and beta-hCG ...