stem cell therapy is a powerful technique for the treatment of a number of diseases. stem cells are derived from different tissue sources, the most important of which are the bone marrow (bm), umbilical cord (uc) blood and liver. human uc mesenchymal stem cells (huc-mscs) are multipotent, non-hematopoietic stem cells that have the ability to self-renew and differentiate into other cells and tis...

the increasing prevalence of chronic diseases, e.g., cardiovascular disease, diabetes and neuronal degenerative disease, present a challenge to find more effective therapies. stem cell-based therapy, including embryonic, umbilical cord blood and adult stem cells provides a rational treatment tool for regenerative medicine and has the potential to revolutionize modern therapy. however, there are...

objective: despite of many benefits, umbilical cord blood (ucb) hematopoietic stem cell (hsc) transplantation is associated with low number of stem cells and slow engraftment; in particular of platelets. so, expanded hscs and co-transfusion of megakaryocyte (mk) progenitor cells can shorten this period. in this study, we evaluated the cytokine conditions for maximum expansion and mk differentia...

introduction: acute myelogenous leukemia (aml) is a clonal  malignant disease of hematopoietic tissue. the early use of  hematopoietic stem cell transplantation (hsct) for aml was for patients with advanced stages of disease, usually while in relapse, in second or subsequent remission, or with resistant disease. patients and methods: from march 1991 until february 2008, 356(65%) registered allo...

Ex vivo expansion of human umbilical cord blood cells (HUCBC) is explored by several investigators to enhance the repopulating potential of HUCBC. The proliferation and expansion of human hematopoietic stem cells (HSC) in ex vivo culture was examined with the goal of generating a suitable clinical protocol for expanding HSC for patient transplantation. Using primary human mesenchymal stem ...

To test the hypothesis that bacterial contamination of menstrual blood could be a local biologic event in the development of endometriosis, menstrual blood was cultured and bacterial endotoxin was measured in menstrual blood and peritoneal fluid. Our results suggest that compared with control women, higher colony formation of Escherichia coli in menstrual blood and endotoxin levels in menstrual...

Background: Cord blood stem cells are a source of very young Away from moral hazard problems, autoimmune reactions, cancer, and adults have the benefits of both a source of embryonic stem cells. Materials and Methods: In this cross - sectional study, 100 pregnant women with the range 45-19 years of age participated The questionnaire included 15 questions based on information and knowledge facto...

allogeneic hematopoietic stem cell transplantation (hsct) is the most effective therapy to prevent relapse in acute lymphocytic leukemia (all). this benefit is affected by non-relapse mortality (nrm) due to complications such as graft versus host disease (gvhd). a new approach in analyzing time-dependent covariates in competing risks is landmark analysis. so, the aim of this study is to evaluat...