نتایج جستجو برای: mesenchymal tumor
تعداد نتایج: 479087 فیلتر نتایج به سال:
Mesenchymal stem/stromal cells (MSC) are multipotent precursors endowed with the ability to home to primary and metastatic tumor sites, where they can integrate into the tumor-associated stroma. However, molecular mechanisms and outcome of their interaction with cancer cells have not been fully clarified. In this study, we investigated the effects mediated by bone marrow-derived MSC on human co...
Introduction. Inflammatory myofibroblastic tumor is a mesenchymal neoplasm with an aggressive potential and tendency for recurrence. It known to occur in variety of locations, including the female genital tract. The objective this study was provide overview clinical, histopathological, immunohistochemical molecular features inflammatory tumor, emphasizing diagnostic pitfalls Case Report. diagno...
Lipoma is a benign mesenchymal tumor that develops in abundant areas of fatty tissue. Its location the hand rare. The first lipoma was described by Stein 1959. targeted localizations hands concern thenar and hypothenar eminences, more rarely digital localizations. clinical symptomatology varies according to location, with progressively increasing size leading hold on mobility fingers risk neuro...
Overexpression and enhanced activation of the epidermal growth factor receptor (EGFR) is frequently observed in human carcinomas. Inhibitors of EGFR signaling have shown clinical utility; however, understanding response at the molecular level is important to define patient subsets most likely to benefit, as well as to support the rational design of drug combinations. Pancreatic and colorectal t...
Phosphaturic mesenchymal tumor (PMT) is a rare and small tumor leading to oncogenic osteomalacia and deriving mostly from benign mesenchymal origin. The tumor may originate in any part of the body such as soft tissue or bone site, but is more frequent in the upper and lower extremities and craniofacial sinuses. Its most common type is oncogenic osteomalacia (OO) associated phosphaturic mesenchy...
UNLABELLED Glioblastoma (GBM) is a highly aggressive brain cancer characterized by local invasion and angiogenic recruitment, yet metastatic dissemination is extremely rare. Here, we adapted a microfluidic device to deplete hematopoietic cells from blood specimens of patients with GBM, uncovering evidence of circulating brain tumor cells (CTC). Staining and scoring criteria for GBM CTCs were fi...
BACKGROUND Mounting clinical and experimental evidence suggests that the shift of carcinomas towards a mesenchymal phenotype is a common paradigm for both resistance to therapy and tumor recurrence. However, the mesenchymalization of carcinomas has not yet entered clinical practice as a crucial diagnostic paradigm. METHODOLOGY/PRINCIPAL FINDINGS By integrating in silico and in vitro studies w...
Uterine sarcomas are rare female genital tract malignancies. Mullerian adenosarcoma is a biphasic malignant mesenchymal tumor comprising of benign glandular and (usually low grade) stromal component, both which integral neoplastic constituents the tumor.[1] This represents less than 8% uterine sarcomas. About 200 cases have been reported in literature so far [2] 22 case were from India. Adenosa...
The nasal cavity harbors an enormous variety of neoplasms, including epithelial and mesenchymal tumors. Hemangioma is an infrequent mesenchymal tumor of the nasal cavity, mostly arising in the mucosa and rarely in the bones. We describe the case of a 73-year-old woman who was referred to our hospital with a tumor in her left nasal cavity. The tumor originated from the left inferior turbinate. H...
Hepatic mesenchymal hamartoma is a rare benign tumor. We present an unusual case of a fetal abdominal cyst, later diagnosed histopathologically to be mesenchymal hamartoma of liver. The organ of origin was indeterminate on both prenatal and postnatal ultrasounds. As there are no specific sonological findings, whenever a large multicystic fetal abdominal cyst is seen, mesenchymal hamartoma shoul...
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