نتایج جستجو برای: methylenedioxymethamphetamine

تعداد نتایج: 1065  

Journal: :Acta crystallographica Section B, Structural science, crystal engineering and materials 2015
Lauren E Connor Amit Delori Ian B Hutchison Niamh Nic Daeid Oliver B Sutcliffe Iain D H Oswald

MDMA (3,4-methylenedioxymethamphetamine) is a Class A substance that is usually found in a tableted form. It is only observed in one orthorhombic polymorph under ambient conditions. It shows slight positional disorder around the methlyenedioxy ring which persists during compression up to 6.66 GPa. The crystal quality deteriorates above 6.66 GPa where the hydrostatic limit of the pressure-transm...

2016
Kaeli Zimmermann Benjamin Becker

MDMA (3,4-methylenedioxymethamphetamine), often referred to as ‘ecstasy’, has been shown to selectively and persistently impair central serotonergic neurotransmission in laboratory animals. As of recent, evidence in human studies has suggested a link between recreational ecstasy use and a disruption of the brain’s serotonergic system. However, human neurocognitive and neuroimaging studies have ...

2001
Kevin T. Finnegan John J. Skratt James W. Langston

'.'dj we explored _he role of report that dextr0rphan _,L in rat brain. This observ The N-methyl-D-aspartate (NMDA) receptor MDMA-ind ea neurot Male Sprague-Dawle antagonist, dextrorphan, prevents the neurotoxic mic MDMA was synthe effects of 3,4-methylenedioxymethamphetamine t4j.Dextrorphan was ge Groups of rats (n= 6) w ¥, (MDMA) in rats trorphan alone (45 mgj increasing doses of dext '_3I Ke...

Journal: :Behavioural pharmacology 2011
Adam Stewart Russell Riehl Keith Wong Jeremy Green Jessica Cosgrove Karoly Vollmer Evan Kyzar Peter Hart Alexander Allain Jonathan Cachat Siddharth Gaikwad Molly Hook Kate Rhymes Alan Newman Eli Utterback Katie Chang Allan V Kalueff

3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') is a potent psychedelic drug inducing euphoria and hypersociability in humans, as well as hyperactivity and anxiety in rodents. Adult zebrafish (Danio rerio) have become a widely used species in neurobehavioral research. Here, we explore the effects of a wide range (0.25-120 mg/l) of acute MDMA doses on zebrafish behavior in the novel tank tes...

Journal: :Forensic science international 2003
Pascal Gimeno Fabrice Besacier Huguette Chaudron-Thozet

The extraction of impurities from illegally produced 3,4-methylenedioxymethamphetamine (MDMA) has been studied in order to optimize the parameters. Two different MDMA samples were used. Particular attention was paid to the influence of the pH, the evaporation step, and the sample storage. The method used was an extraction of impurities by diethyl ether from a buffer solution at pH 11.5, followe...

2017
BB Yazar‐Klosinski MC Mithoefer

Phase II trials of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy have demonstrated initial safety and efficacy for treatment of posttraumatic stress disorder (PTSD), with potential for expansion to depression and anxiety disorders. In these trials, single doses of MDMA are administered in a model of medication-assisted psychotherapy, differing from trials involving daily drug ...

Journal: :cell journal 0

objective: the spice zingiber officinale or ginger possesses antioxidant activity and neuroprotective effects. the effects of this traditional herbal medicine on 3,4-methylenedioxymethamphetamine (mdma) induced neurotoxicity have not yet been studied. the present study considers the effects of zingiber officinale on mdma-induced spatial memory impairment and apoptosis in the hippocampus of male...

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