This study aimed to estimate the disease burden of methylmercury for children born in Germany in the year 2014. Humans are mainly exposed to methylmercury when they eat fish or seafood. Prenatal methylmercury exposure is associated with IQ loss. To quantify this disease burden, we used Monte Carlo simulation to estimate the incidence of mild and severe mental retardation in children born to mot...

BACKGROUND Fish and seafood provide important nutrients but may also contain toxic contaminants, such as methylmercury. Advisories against pollutants may therefore conflict with dietary recommendations. In resolving this conundrum, most epidemiologic studies provide little guidance because they address either nutrient benefits or mercury toxicity, not both. OBJECTIVES Impact on the same healt...

..................................................................................................................... 23 Introduction ................................................................................................................ 25 Methods...................................................................................................................... 28 Subjects ............

We reevaluate the treatment of mercury poisoning, incorporating recent advances in understanding toxicity and mercury:selenium interaction. This review focuses on: 1) role, limitations benefits chelation (Unithiol, succimer N-Acetylcysteine); 2) role selenium supplementation; 3) how different forms are impacted by use selenium. Unithiol produce increases urinary excretion to a lesser degree blo...

Artisanal gold-mining activities in the Philippines have proliferated since the early 1980s. Presently, environmental and health monitoring conducted by several governmental agencies is limited to the determination of total mercury only. Previous studies undertaken focused mainly on the exposure of adults and workers to mercury during mining/processing operations. However, in one area in Mindan...

Inuit people living in Canada’s Nunavik region consume large doses of methylmercury through their traditional diet, mostly from sea mammal meat. A new study set out looking for evidence of links between these native communities’ exposure to the toxic metal and heart diseases [EHP 118(8):1077–1083; Ayotte et al.]. The results suggested an inhibitory effect of methylmercury on paraoxonase 1 (PON1...

Inuit people living in Canada’s Nunavik region consume large doses of methylmercury through their traditional diet, mostly from sea mammal meat. A new study set out looking for evidence of links between these native communities’ exposure to the toxic metal and heart diseases [EHP 119(8):1077–1083; Ayotte et al.]. The results suggested an inhibitory effect of methylmercury on paraoxonase 1 (PON1...

FOREWORD This report provides recommended guidelines for consumption of fish from Lake Pillsbury (Lake County). These guidelines are provided to the public as a result of findings of high levels of mercury in fish tested from Lake Pillsbury. These recommendations are provided to protect against possible adverse health effects that may result from consumption of mercury-contaminated fish. The re...

Nicotinamide-(S-methylmercury-thioinosine) dinucleotide was formed by reaction of nicotinamide-(6-thiopurine) dinucleotide with methylmercury chloride. The compound exhibits coenzyme properties in the test with LDH (Km=1.5 X 10(-4) M, Vmax=12500) and LADH (Km=1.7 X 10(-4) M, Vmax=27) and inactivates YADH and GAPDH. From incubations with LDH and LADH the mercury containing coenzyme could be reg...

saltwater fish. In some lakes, rivers, and coastal waters in California, methylmercury has been found in some types of fish at concentrations that may be harmful to human health. The Office of Environmental Health Hazard Assessment (OEHHA) has issued health advisories to fishers and their families giving recommendations on how much of the affected fish in these areas can be safely eaten. In the...