Amiodarone is a viable drug for preventing sudden cardiac death, particularly during the first year after MI. If larger trials confirm the aforementioned prospective trials of Ceremuzynski et al, Cairns et al, and the BASIS trial, the efficacy of amiodarone would outweigh the risk of its side effects during the first year after MI. Based on the long-term observation from the BASIS trial, the du...

We have developed a general quenched-flow approach to study platelet function as early as 0.3 seconds after stimulation. Phosphorylation of 20and 40-kd proteins has been analyzed during the first five seconds of platelet response to thrombin from 0.1 to 5.0 U/mi and compared with the progress of aggregation and serotonin secretion. The onset time for aggregation and phosphorylation of both prot...

The death of P. I. Tchaikovsky (1840 - 1893) excites imagination even today. According to the "official scenario", Tchaikovsky had suffered from abdominal colic before being infected with cholera. On 2 November 1893, he drank a glass of unboiled water. A few hours later, he had diarrhoea and started vomiting. The following day anuria occured. He lost consciousness and died on 6 November (or on ...

Background: Simultaneous electrocardiographic (ECG) changes are seen in hemorrhagic brain events even in the absence of associated myocardial infarction (MI). This study was designed to assess the role of ECG changes to predict true MI in patients with hemorrhagic brain trauma. Methods: Data of 153 patients with traumatic brain injury and concomitant ECG changes were recorded. Enzyme study w...

Introduction: Acute myocardial infarction (MI) indicates irreversible myocardial injury resulting in necrosis of a significant portion of myocardium. MI is associated with high mortality. The difference between the signs of MI in each gender is unclear. The aim of this study was to describe gender-associated differences in symptom presentation after acute MI. Methods: This analytic-descri...

background: ischemic heart disease and acute myocardial infarction is one of the most dramatic manifestations in one of the most investigated fields in the past few decades. in this study, the prognostic value of white blood cells count in patients with myocardial infarction (mi) was investigated in a six months follow-up. methods: in this cohort study, 106 patients with mi were investigated. w...