A 58-year-old male, who had type II diabetes and was on haemodialysis (HD) for 3 years, was referred for management of refractory hyperparathyroidism in 2006. In 2003, he started HD due to diabetic renal failure, after which vitamin D analogue together with oral calcium carbonate and sevelamer hydrochloride was administered, so that serum calcium and phosphate levels were controlled properly. S...

An 81-year-old man was incidentally found to have a posterior mediastinal lesion measuring 25 19 mm behind the trachea and lateral to the esophagus on computed tomography of the chest (Fig 1A, arrow). Parathyroid scintigraphy with Tc-MIBI (technetium with the ligand methoxyisobutylisonitrile) showed persistent focal activity in the posterior mediastinum along the left lateral aspect of the esop...

An 80-year-old man presented with progressive fatigue. Blood tests showed that serum calcium was increased (2.93 mmol/l, normal range 2.20–2.55 mmol/l) and serum concentration of intact parathyroid hormone (iPTH) inappropriately high (198 pg/ml, normal range 15-85 pg/ml). Neck ultrasonography and Tc-MIBI scintigraphy revealed a right parathyroid adenoma and a multinodular goiter. Serum calciton...

Aldosterone-producing adrenocortical carcinomas are an extremely rare cause of hyperaldosteronism (<1%). Coexistence of different endocrine tumors warrants additional screening for multiple endocrine neoplasia syndromes, especially in young patients with large or malignant masses. We present the case of a 40-year-old man with a history of hypertension that presented with an incidental left adre...

Background: Local ablative treatments play an important role for patients who cannot be treated surgically. Radiofrequency ablation is a well-established alternative to surgical treatment of thyroid nodules, however it also has disadvantages. Microwave ablation (MWA) is a new minimally invasive treatment promising several improvements. The aim of this retrospective study was to evaluate the eff...

We report an instructive case of primary hyperparathyroidism in which cyclical secretion of PTH may have caused repeated hypercalcemic crises followed by temporary remission with a spontaneous drop in PTH. A 64-year-old man was admitted to our hospital twice with severe hypercalcemic crisis (corrected calcium (cCa) 15.0 mg/dl and 16.7 mg/dl) accompanied by an increase in intact PTH (220 pg/ml a...

A 42-year-old man was referred to our hospital due to chest pain, diabetes mellitus, and sensorineural hearing loss. Transthoracic echocardiography revealed diffuse left ventricular hypokinesis. He was diagnosed with mitochondrial disease and a c.A3243G mutation was identified in his mitochondrial DNA. This case of mitochondrial cardiomyopathy demonstrated a low uptake of 123I-BMIPP, while the ...

 Background: Bilateral neck exploration is the gold standard for parathyroid adenoma localization in primary hyperparathyroidism. But surgeons do not have adequate experience for accurate surgical exploration and new methods are developed for surgery like unilateral exploration and minimally invasive surgery, thus, preoperative localization could reduces time and stress in surgical performance....

IMPORTANCE Dynamic computed tomography (CT) is emerging as a first-line alternative to sestamibi scintigraphy for preoperative localization of parathyroid lesions. In recent years, there has been increased concern over the impact of radiation exposure from medical imaging, as well as on the cost of diagnostic medical procedures. An ideal diagnostic procedure would be cost effective while minimi...

introduction:we evaluated the performance of muscle perfusion scan (mps) to assess muscle perfusion reserve (mpr) for prediction of incident diabetic foot ulcerations (dfu). methods: we recruited 41 diabetic patients without any history of dfu. five mci 99mtc-mibi was injected intravenously during repetitive dorsal and plantar right foot flexions. then posterior calves were imaged and the count...