Many clinically relevant congenital malformations arise during mid to late embryonic stages. This period is challenging to image quantitatively in live embryos, necessitating the use of multiple specimens with increased experimental variability. Here we establish X-ray and blood-pool computed tomography (CT) contrast agent toxicity and teratogenesis thresholds for 3D Micro-CT imaging of live av...

Aims Renal Osteodystrophy (ROD) is a systemic disorder that develops early with loss of kidney functions and is manifested by abnormalities in bone metabolism, mineralization and volume. Phosphate binders are a major constituent in chronic kidney disease management. Previous Aluminum and calcium containing phosphate binders were thought to be of detrimental effect on bone histology. The aim of ...

X-ray based micro-computed tomography (CT) and micro-digital subtraction angiography (DSA) are important non-invasive imaging modalities for following tumorogenesis in small animals. To exploit these imaging capabilities further, the two modalities were combined into a single system to provide both morphological and functional data from the same tumor in a single imaging session. The system is ...

Accurate characterization of the inner surface X-ray monocapillary optics (XMCO) is great significance in research. Compared with other methods, micro computed tomography (micro-CT) method has its unique advantages but also some disadvantages, such as a long scanning time, image reconstruction and inconvenient process. In this paper, sparse sampling was proposed to shorten GPU acceleration tech...