Tuberculosis (TB) represents a major public health problem. The growing number of (extensively) multi-drug resistance cases indicates that there is an urgent need for discovery of new anti-TB entities, addressed towards new and specific targets, and continuous development of fast and efficient synthetic strategies to access them easily. Microwave-assisted chemistry is well suited for small-scal...

Microwave-assisted Suzuki-Miyaura cross-coupling reactions have been employed towards the synthesis of three different MAPKAPK2 (MK2) inhibitors to study accelerated aging in Werner syndrome (WS) cells, including the cross-coupling of a 2-chloroquinoline with a 3-pyridinylboronic acid, the coupling of an aryl bromide with an indolylboronic acid and the reaction of a 3-amino-4-bromopyrazole with...

This review article is the second of the comprehensive series on survey of the microwave photochemical and photocatalytic processes, and is focused specially on the microwave-assisted photochemical applications of the electrodeless discharge lamps (EDLs) in organic synthesis. The concept of microwave organic photochemistry is an important issue in synthetic chemistry and material science, and i...

We present measurements on microwave spectroscopy on a double quantum dot with a near-field microwave source. The quantum dots are realized in the two-dimensional electron gas of an AlGaAs/GaAs heterostructure and are weakly coupled in series by a tunneling barrier forming an 'ionic' molecular state. As a microwave source we employ a Josephson oscillator formed by a long Nb/Al-AlO x /Nb junctio...

The first production of defibrillated celluloses from microalgal biomass using acid-free, TEMPO-free and bleach-free hydrothermal microwave processing is reported. Two routes were explored: i. direct process native microalgae (“standard”), ii. scCO2 pre-treatment followed by processing. ScCO2 was investigated as it commonly used to extract lipids generates considerable quantities spent algal bi...

in this search drying characteristics of green pea (pisum satium) with an initial moisture content of 76% (db) was studied in a fluidized bed dryer assisted by microwave heating. four drying air temperatures (30, 40, 50 and 60ºc) and five microwave powers (180, 360, 540, 720 and 900w) were adopted. at each drying operating conditions the volume of green pea was calculated by measuring the three...

Plant extracts having an antiplatelet aggregation activity may be a potential choice for development of antiinflammatory drugs because of their natural origin. The extraction of bioactive compounds being the most crucial step in the commercial development of natural products it is essential to have rapid and efficient phytochemical extraction methods. Extracts of B. monnieri were prepared using...

Multivalent dendrimeric peptides were synthesized via a microwave-assisted Huisgen 1,3-dipolar cycloaddition between azido peptides and dendrimeric alkynes in yields ranging from 46 to 96%.