The continuous shear roll milling can be used for the processing and granulation of gun propellants. Here a mathematical model of the continuous shear roll milling process will be presented along with experimental data collected on live and simulant propellant formulations. The role of the flow boundary condition will be shown to be critical in the processability analysis. The safety aspects wi...

A haptic virtual reality milling simulator using high resolution volumetric data is presented in this paper. We discuss the graphical rendering performed from an iso-surface generated using marching cubes with a hierarchical storage method to optimize for fast dynamic changes to the data during the milling process. We also present a stable proxy-based haptic algorithm used to maintain a tip pos...

Synthesis of nanomaterials by a simple, low cost and in high yield has been a great challenge since the very early development of nanoscience. Various bottom and top down approaches have been developed so far, for the commercial production of nanomaterials. Among all top down approaches, high energy ball milling, has been widely exploited for the synthesis of various nanomaterials, nanograins, ...

A prototype of a haptic and virtual reality simulator has been developed for simulation of the bone milling and material removal process occurring in several operations, e.g. temporal bone surgery or dental milling. The milling phase of an operation is difficult, safety critical and very time consuming. Reduction of operation time by only a few percent would in the long run save society large e...

The research investigates synthesized Nano-structured PbO2 using ball milling. The structure and morphology of the samples were determined in the process of milling by means of XRD and SEM. The size of particles was estimated through DLS analysis. The TEM image of the synthesized powder verifies the achievement of Nano dimensions. Design and analyses of the results using Taguchi methodology rev...

The machining of thin-walled double side freeform component has many challenges in terms of the geometrical complexity, high-requirement accuracy, and especially low stiffness. This paper surveys the filling method during the milling processes of thin-walled double side freeform component. Firstly, the DEFORM-3D was used to analyze and calculate the surface residual stress which provides a theo...

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For a commercially viable recombinant intracellular protein production process, efficient cell lysis and protein release is a major bottleneck. The recovery of recombinant protein, cholesterol oxidase (COD) was studied in a continuous bead milling process. A full factorial response surface methodology (RSM) design was employed and compared to artificial neural networks coupled with genetic algo...

Preparation of drug nanoparticles via wet media milling (nanomilling) is a very versatile drug delivery platform and is suitable for oral, injectable, inhalable, and buccal applications. Wet media milling followed by various drying processes has become a well-established and proven formulation approach especially for bioavailability enhancement of poorly water-soluble drugs. It has several adva...