background peganum harmala, glycyrrhiza glabra, mentha spicata and rosmarinus officinalis are often used in traditional medicine. objectives the current study aimed to screen the antifungal activity of ethanolic extracts of p. harmala, g. glabra, m. spicata and r. officinalis leaves collected from sistan region, iran against fusarium oxysporum. methods minimal inhibitory concentration (mic) and...

Antimicrobial efficacy of flavonoids (free and bound) and crude alkaloids of Lantana camara L. was determined by disc diffusion assay against three bacteria (Escherichia coli, Proteus mirabilis, and Staphylococcus aureus) and two fungi (Candida albicans and Trichophyton mentagrophytes). Minimum inhibitory concentration, minimum bactericidal/fungicidal concentration and total activity were also ...

Investigation of the alcoholic extract of chamomile against growth and production of catalase, Dnase and haemolysin of Staphylococcus aureus (ATCC29213) were the aims of this study In this study, German chamomile was prepared from Tehran agricultural researches center. Extraction was performed by ethanol 85 (Maceration method) then solvent is removed by vacuum distillation system (concentrated ...

Antagonism, determined by isobolograms constructed from data from combinations of ampicillin and chloramphenicol at or below the minimal inhibitory or bactericidal concentrations, was observed against 13 clinical isolates of meningococcus and against one isolate of pneumococcus. Synergy occurred against six strains of pneumococcus and three of meningococcus. Additive effects were noted against ...

In a minimal medium, trimethoprim is merely bacteriostatic on the prototroph Escherichia coli 114. The drug was bactericidal when the amino acids methionine and glycine, plus a purine or purine nucleoside, were also present. This response could be reversed completely when thymine and lysine were added to the culture. Methionine, glycine, and the purine are thought to maintain the integrity of t...

propolis has traditionally been used in curing infections and healing wounds and burns. current researches have shown that propolis has antibacterial, antifungal and antiviral actions however, the pharmacological activity of propolis is highly variable depending on its geographic origin. there have been few studies on the effects of iranian propolis on the oral microorganisms. in this in-vitro ...

Latar belakang. Lactobacillus gasseri merupakan jenis bakteri asam laktat (BAL) yang dapat menghasilkan bakteriosin sebagai suatu senyawa antibakteri. Objektif. untuk mengetahui potensi aktivitas terhadap pertumbuhan Salmonella typhi dengan menilai Kadar Hambat Minimal (KHM) dan Bunuh (KBM). Metode. Penelitian ini dilakukan teknik dilusi menggunakan desain Rancangan Acak Lengkap. Konsentrasi di...

Three consecutive doses of 75 mg of cefoxitin per kg were given intravenously every 6 h (225 mg/kg), in addition to penicillin or ampicillin, to 24 patients on days 4 and 5 and 9 and 10 of therapy for meningitis. Haemophilus influenzae b was isolated from cerebrospinal fluid (CSF) of 21 patients, Streptococcus pneumoniae from 2 patients, and Neisseria meningitidis from 1 patient. The median min...

The antibacterial activity of two bisbenzylisoquinoline alkaloids, tetrandrine (Tet) and demethyltetrandrine (d-Tet), alone and in combination with the antibiotics ampicillin (AMP), azithromycin (AZM), cefazolin (CFZ) and levofloxacin (LEV) against 10 clinical isolates of staphylococcal chromosomal cassette mec (SCCmec) III type methicillin-resistant Staphylococcus aureus (MRSA) was studied. Su...

The rate of inactivation of metronidazole in vitro was determined during the course of time-kill curves against anaerobic and aerobic bacteria in the stationary phase of growth. Metronidazole at a concentration of 10 mug/ml, as measured by bioassay, was rapidly inactivated in broth culture by susceptible anaerobic bacteria (minimum bactericidal concentration </= 3 mug/ml), and this correlated c...