Vol. 25 No. 3, 2013 387 Received June 14, 2012, Revised August 28, 2012, Accepted for publication October 21, 2012 Corresponding author: Gwang Seong Choi, Department of Dermatology, Inha University Hospital, 27 Inhang-ro, Jung-gu, Incheon 400-711, Korea. Tel: 82-32-890-2238, Fax: 82-32-890-2236, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative...

The available minoxidil formulations for topical application suffer with major drawback and requires repeated application. The present study was aimed to investigate the effect of microemulsions and microemulsion based hydrogel-systems (MEHs) for increased percutaneous penetration of minoxidil. Minoxidil microemulsions were developed by conventional titration method using oleic-acid as oil, twe...

Present study was undertaken to assess the potential of Glycerosomes as a novel drug delivery system for topical application of Minoxidil. Pre-formulation studies were done for identification of drug as well as for determination of its physiochemical properties. Spectra of various mixtures of drug and excipients do not show any additional peak thus, indicating compatibility with each other. Gly...

Aim: To evaluate possible results with the stimulation use of minoxidil and the strengthening of hair roots with nutritional cyclical supplements, resulting in increased hair regrowth, without the use of anti androgens and enzyme blockers. Methods: This prospective controlled clinical trial compares the current acknowledged form of treatment for hair loss within two controlled groups for both m...

We examined the effect of endothelium and lipid emulsion on vasodilation induced by minoxidil at a toxic dose determined underlying mechanism. The effects endothelial denudation, NW-nitro-L-arginine methyl ester (L-NAME), methylene blue, 1H-[1,2,4]oxadiazolo[4,3-a] quinoxalin-1-one (ODQ), glibenclamide, alone or in combination, minoxidil-induced endothelium-intact rat aorta were examined. Addit...