نتایج جستجو برای: misclassification
تعداد نتایج: 4685 فیلتر نتایج به سال:
BACKGROUND Genotyping has become more cost-effective and less invasive with the use of buccal cell sampling. However, low or fragmented DNA yields from buccal cells collected using FTA cards often requires additional whole genome amplification to produce sufficient DNA for genotyping. In our case-control study of childhood leukaemia, discordance was found between genotypes derived from blood an...
In epidemiological studies, observed data are often collected subject to misclassification errors. In this paper, we discuss the Bayesian estimation for contingency table with misclassification errors. Employing the exact Bayesian computations to obtain posterior means as estimates, we are faced with computational difficulties. In order to find the posterior distribution, we apply the data augm...
OBJECTIVES Recent genetic association studies have provided convincing evidence that several novel loci and single nucleotide polymorphisms (SNPs) are associated with the risk of developing type 2 diabetes mellitus (T2DM). The aims of this study were: 1) to develop a predictive model of T2DM using genetic and clinical data; and 2) to compare misclassification rates of different models. METHOD...
BACKGROUND Antiretroviral therapy (ART) in resource-limited settings (RLSs) is monitored clinically and immunologically, according to World Health Organization (WHO) or national guidelines. Revised WHO pediatric guidelines were published in 2010, but their ability to accurately identify virological failure is unclear. METHODS We evaluated performance of WHO 2010 guidelines and compared them w...
BACKGROUND Linkage data have now identified several inflammatory bowel disease (IBD) susceptibility loci but these data have not been consistently replicated in independent studies. One potential explanation for this is the possibility that patients enrolled in such studies may have been erroneously classified with respect to their diagnosis. AIMS To determine the rate and type of misclassifi...
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