The mdm17 mutation causes temperature-dependent defects in mitochondrial inheritance, mitochondrial morphology, and the maintenance of mitochondrial DNA in the yeast Saccharomyces cerevisiae. Defects in mitochondrial transmission to daughter buds and changes in mitochondrial morphology were apparent within 30 min after shifting cells to 37 degrees C, while loss of the mitochondrial genome occur...

The PLA2G6 gene encodes a group VIA calcium-independent phospholipase A2 beta enzyme that selectively hydrolyses glycerophospholipids to release free fatty acids. Mutations in PLA2G6 have been associated with disorders such as infantile neuroaxonal dystrophy, neurodegeneration with brain iron accumulation type II and Karak syndrome. More recently, PLA2G6 was identified as the causative gene in ...

Mitochondrial dysfunction has been observed in skeletal muscle of people with diabetes and insulin-resistant individuals. Furthermore, inherited mutations in mitochondrial DNA can cause a rare form of diabetes. However, it is unclear whether mitochondrial dysfunction is a primary cause of the common form of diabetes. To date, common genetic variants robustly associated with type 2 diabetes (T2D...

A mitochondrion is a cellular organelle able to produce energy in the form of adenosine triphosphate (ATP). As nucleus, mitochondria contain their own genome: mitochondrial DNA (mtDNA). This genome particularly susceptible mutations that are at basis multitude disorders, especially those affecting heart, central nervous system and muscles. Conventional clinical practice applied diseases very li...

The mitochondrial genomes of flowering plants possess a promiscuous proclivity for taking up sequences from the chloroplast genome. All characterized chloroplast integrants exist apart from native mitochondrial genes, and only a few, involving chloroplast tRNA genes that have functionally supplanted their mitochondrial counterparts, appear to be of functional consequence. We developed a novel c...

We present a genome assembly from an individual male Hedya salicella (the White-backed Marble; Arthropoda; Insecta; Lepidoptera; Tortricidae). The sequence is 742.3 megabases in span. Most of the scaffolded into 25 chromosomal pseudomolecules, including Z sex chromosome. mitochondrial has also been assembled and 16.3 kilobases length. Gene annotation this on Ense...

The genus Toxares Haliday, 1840 is a small taxon of Aphidiinae, consisting four valid species in the world. One recorded as new to science from South Korea, this study. Descriptions and illustrations species, T. koreanus sp. nov. , are provided, together with their mitochondrial cytochrome c oxidase subunit I (COI) D2 region nuclear gene for 28S rRNA ( ) sequences. phylogenetic tree reconstruct...

Two new Uromunna species, mundongensis sp. n. and jejuensis n., are described from the Korean Peninsula, representing first record of genus in waters. Genetic analyses using two mitochondrial (COI, Cytb) one ribosomal (18S rRNA) gene allowed us to confirm high pair-wise interspecific differences with establishment reliable barcoding gaps COI (19.9%) 18S (0.4%) between species. Finally, phylogen...

We present a genome assembly from an individual male Lysandra coridon (the Chalkhill Blue; Arthropoda; Insecta; Lepidoptera; Lycaenidae). The sequence is 541 megabases in span. Most of the scaffolded into 90 chromosomal pseudomolecules, including assembled Z sex chromosome. mitochondrial has also been and 15.4 kilobases length. Gene annotation this on Ensembl ide...