نتایج جستجو برای: mitochondrial permeability transition pore
تعداد نتایج: 470075 فیلتر نتایج به سال:
Subject codes: [95] Endothelium/vascular type [129] Angiogenesis [140] Energy metabolism [145] Genetically altered mice ABSTRACT Rationale: The mitochondrial permeability transition pore (mPTP) is a well-known initiator of cell death that is increasingly recognized as a physiological modulator of cellular metabolism. Objective: We sought to identify how the genetic deletion of a key regulatory ...
Mitochondrial permeability transition (PT) involves the formation of proteaceous, regulated pores, probably by apposition of inner and outer mitochondrial membrane proteins which cooperate to form the mitochondrial megachannel (= mitochondrial PT pore). PT has important metabolic consequences, namely the collapse of the mitochondrial transmembrane potential, uncoupling of the respiratory chain,...
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