Osteoarthritis is the fourth leading cause of disability affecting more than 300 million people around globe. In this disease, chondrocytes responsible for growth and maintenance articular joints start to deplete due rogue involvement phosphoinositide 3-kinase, protein kinase-B p38 mitogenactivated kinases. Presently, there are medications providing symptomatic treatment, however, they cannot t...

Theabrownin is a heterogeneous polyphenolic compound, obtained from fermented dark teas, with many bioactive functions. However, the role of theabrownin in skin photoaging remains unclear. In this study, we investigated whether modulates ultraviolet B (UVB)-induced matrix metalloprotease-1 (MMP-1) expression HaCaT keratinocytes. exerted antioxidant properties, which resulted scavenging intracel...

Qing’E pills are a classical formula in traditional Chinese medicine that has the effect of tonifying kidneys and strengthening bones, first appearing tonic formulae prescriptions peaceful benevolent dispensary (10th century CE). To preliminarily elucidate potential mechanisms treatment postmenopausal osteoporosis based on network pharmacology. The principal components corresponding protein tar...