Alterations in matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) have been implicated in adverse left ventricular (LV) remodeling after myocardial infarction (MI). However, the direct mechanistic role of TIMPs in the post-MI remodeling process has not been completely established. The goal of this project was to define the effects of altering endogenous MMP inhibitory contro...

Handwriting analysis is useful for understanding the personality characteristics through the patterns created by the handwriting and can reveal features such as mental and emotional instability. On the other hand, it is difficult to determine the personality, especially when it is associated with the law because there is no threshold or scale being able to make detailed results of the analysis....

The interpretation of MMPI (Hathaway & McKinley, 1943) profiles has emphasized a language of pathological attribution that often serves the interests of clinical description and actuarial prediction better than those of individual case formulation and an understanding of the adaptive forces involved in the production of symptomatic behavior. In this article, I illustrate a contrasting approach,...

The objectives of this study were to (1) determine the frequency of the MMPI profile types identified by Marks and Seeman (1963) among chronic pain patients, and (2) determine the predictive validity of the profile types found. One thousand, six hundred and seven valid MMPIs from chronic pain patients seen at a multidisciplinary pain center for possible inpatient treatment were categorized into...

The current study examined the utility of the recently released Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008) validity scales to detect feigned psychopathology in a criminal forensic setting. We used a known-groups design with the Structured Interview of Reported Symptoms (SIRS; Rogers, Bagby, & Dickens, 1992) as the external criterion ...

In the current study, we evaluated the associations between the Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008) scale scores and the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5; American Psychiatric Association, 2013) Section II personality disorder (PD) criterion counts in inpatient and forensic psychiatric samp...

Self-report plays a primary but not exclusive role in pain assessment. As is true of all self-reported experiences, under certain circumstances, the report of chronic pain can be distorted and misrepresented. There are unique challenges associated with the detection and assessment of malingering or self-report distortion in the evaluation of chronic pain. The current paper provides a rationale ...

The purpose of the present study was to first examine whether childhood abuse predicts symptom complexity, as indicated by the number of clinically elevated scales on the MMPI-2 in an adult clinical sample. Secondly, we investigated whether emotion regulation difficulties mediated the relationship between childhood abuse and symptom complexity. A total of 162 adult outpatients not presenting wi...