In humans, the L-cysteine desulfurase NFS1 plays a crucial role in the mitochondrial iron-sulfur cluster biosynthesis and in the thiomodification of mitochondrial and cytosolic tRNAs. We have previously demonstrated that purified NFS1 is able to transfer sulfur to the C-terminal domain of MOCS3, a cytosolic protein involved in molybdenum cofactor biosynthesis and tRNA thiolation. However, no di...

Background Right ventricular (RV) T1 quantification is desirable in managing congenital heart disease and pulmonary hypertension patients where RV fibrosis is implicated. RV T1 quantification is technically difficult because of the thin trabeculated mobile wall of complex geometry, impacted by adjacent blood and epicardial fat, plus proximity to sternal wires in some cases. Prior work has measu...

With appropriate geometry configurations, bistatic Synthetic Aperture Radar (SAR) can break through the limitations of monostatic SAR on forward-looking imaging. Thanks to such a capability, bistatic forward-looking SAR (BFSAR) has extensive potential applications. For the focusing problem of BFSAR, wavenumber-domain algorithm is accepted as the ideal solution. However, in practical application...

This paper proposes three novel feature extraction approaches for human activity recognition in videos. The proposed solutions are based on video coding concepts including motion compensations and variables. We use these features with deep learning model generation classification, hence the ViCo-MoCo-DL abbreviation which stands Video Coding Motion Compensation Deep Learning. These fused terms ...

The terpenoid gossypol, a secondary metabolite found in the cotton plant, is synthesized by a free radical dimerization of hemigossypol. Gossypol exists as an atropisomeric mixture because of restricted rotation around the central binaphthyl bond. The dimerization of hemigossypol is regiospecific in cotton. In the case of some moco cotton, the dimerization also exhibits a high level of stereose...

Molybdenum cofactor (Moco) biosynthesis is linked to c-Jun N-terminal kinase (JNK) signaling in Drosophila through MoaE, a molybdopterin (MPT) synthase subunit that is also a component of the Ada Two A containing (ATAC) acetyltransferase complex. Here, we show that human MPT synthase and ATAC inhibited PKR, a double-stranded RNA-dependent protein kinase, to facilitate translation initiation of ...

Introducción: la cefalea rinogénica es secundaria al contacto permanente de mucosa nasal y puede ser secundario a concha bullosa, si se infecta mucocele o mucopiocele. Caso clínico: paciente 34 años con hemicraneal izquierda, dolor periocular ipsilateral, congestión rinorrea hialina cambios en consistencia coloración del moco. En tomografía computarizada (TAC) senos paranasales (SPN) desviación...

El asma debido a sus características clínicas, fisiológicas y patológicas se define como una enfermedad heterogénea, caracterizada por inflamación crónica de las vías aéreas, con manifestaciones lo son sibilancias, dificultad respiratoria, opresión torácica tos, junto limitación variable del flujo aéreo espiratorio, cuales varían en su intensidad largo tiempo. La la vía aérea está asociada un a...

An organism’s metabolome is the cataloguing of the entire set of metabolites found in the organism. It is dynamic and thus just a snapshot of the processes going on in the organism at one specific time point. When combined with other ‘‘omics’’ data, a more complete understanding of the organism emerges (Fiehn et al., 2000). However, several technical challenges to obtaining a metabolomic profil...