Cancer of unknown primary (CUP) ranges within top 10 cancers in both incidence and mortality. As primary identification is crucial to choosing treatment, guidelines on CUP emphasize the diagnostic strategy. Whether guidelines are complied with, or if they are indeed helpful, is however unclear. We compared procedures performed in suspected CUP patients with recommendations of national guideline...

PURPOSE To determine whether photorefractive keratectomy (PRK) has a significant effect on optic nerve head (ONH) parameters and peripapillary retinal nerve fiber layer (RNFL) thickness measured by the Heidelberg Retina Tomograph 3 (Heidelberg Engineering GmbH, Heidelberg, Germany) in eyes with low to moderate myopia. METHODS This prospective, interventional case series, includes 43 consecuti...

CUP syndrome (cancer of unknown primary) describes the presence histologically proven metastases in an primary tumor. It affects about 3–5% all tumor patients. The search for makes extensive diagnostics necessary. However, 2/3 patients original is not discovered. Operation, radiation, chemotherapy and, some cases, targeted therapy are available as treatment. prognosis unfavorable.

INTRODUCTION Malposition of the acetabular component is a risk factor for postoperative dislocation after total hip arthroplasty (THA)[1]. Current radiographic techniques for assessing cup anteversion have been developed, but they have limitations[2]. The purpose of this study is to investigate the effect of and reduce the error caused by various pelvis postures on cup anteversion measurement. ...

Initial stability is an essential prerequisite to achieve osseointegration of press-fit acetabular cups in total hip replacements. Most in vitro methods that assess cup stability do not reproduce physiological loading conditions and use simplified acetabular models with a spherical cavity. The aim of this study was to investigate the effect of bone density and acetabular geometry on cup stabili...

BACKGROUND To prevent breastfeeding problems, cup-feeding has been recommended as a method of providing medically necessary supplemental feedings to breastfed infants. OBJECTIVES To compare amounts ingested, administration time, and infant physiologic stability during cup-, bottle-, and breastfeeding. DESIGN/METHODS A total of 98 term, healthy newborns were randomized to either cup-feeding ...

BACKGROUND Cotyloplasty is a technique that involves making a perforation of the medial wall of a shallow acetabulum and then inserting an acetabular cup with the medial aspect of its dome beyond the Kohler line. The purpose of this study was to evaluate the results of cementless total hip arthroplasty (THA) using cotyloplasty with focusing on the amount of medial cup protrusion. METHODS Sixt...