backround laryngopharyngeal reflux (lpr) is the backflow of stomach contents above upper esophageal sphincter, into the pharynx, larynx, and upper aerodigestive system. objectives in this study, effects of omeprazole over voice quality in muscle tension dysphonia with laryngopharyngeal reflux was ınvestigated. patients and methods nine patients, 7 males and 2 females, aged between 27-43 (mean a...

Nocturnal gastro-oesophageal reflux may be important in the pathogenesis of reflux oesophagitis. This study aimed to determine whether: (1) gastro-oesophageal reflux occurs during sleep in patients with reflux oesophagitis and, if so, to explore the mechanism, and (2) the sleep pattern of patients with oesophagitis is different from that of control subjects. After a standard evening meal, simul...

The aim of this study was to compare acid reflux in 16 patients with uncomplicated Barrett's oesophagus with 37 patients with reflux oesophagitis and 10 control subjects of comparable age. All patients had 24 hour ambulatory pH monitoring within one week of endoscopy. The controls differed significantly from the other groups in all indices of reflux but there was no difference between the Barre...

The prevalence of lower extremity ulceration secondary to chronic venous disease (CVD) in European and Western populations is estimated to be 0.5% to 1%.12 Approximately 12% to 14% of patients with CVD in recent series 3’4have venous ulcers (clinical classes C5 and C6). Despite the high prevalence and the significant morbidity of this problem, it has always been relatively neglected. Even curre...

We investigated comparison according to reflux esophagitis and non-erosive reflux disease about "daily" symptom improvement for proton pump inhibitor treatment. We enrolled 57 reflux esophagitis and 90 non-erosive reflux disease patients. They took rabeprazole 10 mg/day for 28 days and completed "daily" in the Frequency Scale for the Symptoms of GERD from baseline until day 14, and after 28 day...

BACKGROUND The importance of weakly acidic and weakly alkaline reflux in gastro-oesophageal reflux disease (GERD) is gaining recognition. AIM To quantify the proportions of reflux episodes that are acidic (pH <4), weakly acidic (pH 4-7) and weakly alkaline (pH >7) in adult patients with GERD, and to evaluate their correlation with symptoms. METHODS Studies were identified by systematic PubM...

BACKGROUND People with proven gastroesophageal reflux disease may also experience symptoms such as voice loss, chronic cough, globus, and sore throat. These laryngopharyngeal reflux symptoms have been reported to respond to prolonged proton pump inhibitor therapy, but the Hill approach to resolving these specific individual symptoms has not been widely reported in surgical literature. METHODS...

IS GASTROESOPHAGEAL REFLUX DISEASE INFLUENCED BY DUODENOGASTRIC REFLUX ? (Abstract): BACKGROUND: It is well known that the gastroesophageal reflux is a frequent disease in medical practice. A lot of factors are involved in its pathogenesis. The aim of our study was to find out if the duodenogastric reflux is one of these factors. We also looked for the pathological conditions associated with du...

We studied eight patients with gastro-oesophageal reflux disease to compare the frequency and mechanism of reflux in the upright and supine positions. Simultaneous oesophageal manometry and pH studies were performed on two separate days in each subject in the fasting and postprandial periods. The frequency of reflux tended to be higher in the upright position. The most prevalent mechanism of re...

G ASTROESOPHAGEAL reflux disease (GORD) is the most common oesophageal disease. Besides the typical presentation of heartburn and acid regurgitation, GORD can cause atypical symptoms. An estimated 20–60% of patients with GORD have head and neck symptoms without heartburn 1 and at least 10% of patients who attend a general ear, nose and throat clinic will have symptoms or signs related to reflux...